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Receptor binding domain (RBD) antibodies contribute more to SARS-CoV-2 neutralization when target cells express high levels of ACE2.
Farrell AG, Dadonaite B, Greaney AJ, Eguia R, Loes AN, Franko NM, Logue J, Carreño JM, Abbad A, Chu HY, Matreyek KA, Bloom JD. Farrell AG, et al. Among authors: loes an. bioRxiv [Preprint]. 2022 Aug 30:2022.08.29.505713. doi: 10.1101/2022.08.29.505713. bioRxiv. 2022. Update in: Viruses. 2022 Sep 16;14(9):2061. doi: 10.3390/v14092061. PMID: 36093349 Free PMC article. Updated. Preprint.
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition.
Greaney AJ, Starr TN, Gilchuk P, Zost SJ, Binshtein E, Loes AN, Hilton SK, Huddleston J, Eguia R, Crawford KHD, Dingens AS, Nargi RS, Sutton RE, Suryadevara N, Rothlauf PW, Liu Z, Whelan SPJ, Carnahan RH, Crowe JE Jr, Bloom JD. Greaney AJ, et al. Among authors: loes an. bioRxiv [Preprint]. 2020 Sep 28:2020.09.10.292078. doi: 10.1101/2020.09.10.292078. bioRxiv. 2020. Update in: Cell Host Microbe. 2021 Jan 13;29(1):44-57.e9. doi: 10.1016/j.chom.2020.11.007. PMID: 32935107 Free PMC article. Updated. Preprint.
27 results