Abrams SI - Search Results

1

Mitigating the prevalence and function of myeloid-derived suppressor cells by redirecting myeloid differentiation using a novel immune modulator.

Oliver L, Alvarez R, Diaz R, Valdés A, Colligan SH, Nemeth MJ, Twum DYF, Fernández A, Fernández-Medina O, Carlson LM, Yu H, Eng KH, Hensen ML, Rábade-Chediak ML, Fernández LE, Lee KP, Perez L, Muhitch JB, Mesa C, Abrams SI. Oliver L, et al. Among authors: abrams si. J Immunother Cancer. 2022 Sep;10(9):e004710. doi: 10.1136/jitc-2022-004710. J Immunother Cancer. 2022. PMID: 36150744 Free PMC article. Clinical Trial.

2

A multi-functional role of interferon regulatory factor-8 in solid tumor and myeloid cell biology.

Abrams SI. Abrams SI. Immunol Res. 2010 Mar;46(1-3):59-71. doi: 10.1007/s12026-009-8125-6. Immunol Res. 2010. PMID: 19756408 Review.

3

Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice.

Godoy HE, Khan AN, Vethanayagam RR, Grimm MJ, Singel KL, Kolomeyevskaya N, Sexton KJ, Parameswaran A, Abrams SI, Odunsi K, Segal BH. Godoy HE, et al. Among authors: abrams si. PLoS One. 2013 Jul 26;8(7):e69631. doi: 10.1371/journal.pone.0069631. Print 2013. PLoS One. 2013. PMID: 23922763 Free PMC article.

4

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis.

Waight JD, Netherby C, Hensen ML, Miller A, Hu Q, Liu S, Bogner PN, Farren MR, Lee KP, Liu K, Abrams SI. Waight JD, et al. Among authors: abrams si. J Clin Invest. 2013 Oct;123(10):4464-78. doi: 10.1172/JCI68189. Epub 2013 Sep 16. J Clin Invest. 2013. PMID: 24091328 Free PMC article.

5

Tumor-induced STAT3 signaling in myeloid cells impairs dendritic cell generation by decreasing PKCβII abundance.

Farren MR, Carlson LM, Netherby CS, Lindner I, Li PK, Gabrilovich DI, Abrams SI, Lee KP. Farren MR, et al. Among authors: abrams si. Sci Signal. 2014 Feb 18;7(313):ra16. doi: 10.1126/scisignal.2004656. Sci Signal. 2014. PMID: 24550541 Free PMC article.

6

Regulation of the interferon regulatory factor-8 (IRF-8) tumor suppressor gene by the signal transducer and activator of transcription 5 (STAT5) transcription factor in chronic myeloid leukemia.

Waight JD, Banik D, Griffiths EA, Nemeth MJ, Abrams SI. Waight JD, et al. Among authors: abrams si. J Biol Chem. 2014 May 30;289(22):15642-52. doi: 10.1074/jbc.M113.544320. Epub 2014 Apr 21. J Biol Chem. 2014. PMID: 24753251 Free PMC article.

7

Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models.

Shen L, Sundstedt A, Ciesielski M, Miles KM, Celander M, Adelaiye R, Orillion A, Ciamporcero E, Ramakrishnan S, Ellis L, Fenstermaker R, Abrams SI, Eriksson H, Leanderson T, Olsson A, Pili R. Shen L, et al. Among authors: abrams si. Cancer Immunol Res. 2015 Feb;3(2):136-48. doi: 10.1158/2326-6066.CIR-14-0036. Epub 2014 Nov 4. Cancer Immunol Res. 2015. PMID: 25370534 Free PMC article.

8

Tumor-induced myeloid dysfunction and its implications for cancer immunotherapy.

Messmer MN, Netherby CS, Banik D, Abrams SI. Messmer MN, et al. Among authors: abrams si. Cancer Immunol Immunother. 2015 Jan;64(1):1-13. doi: 10.1007/s00262-014-1639-3. Epub 2014 Nov 29. Cancer Immunol Immunother. 2015. PMID: 25432147 Free PMC article. Review.

9

Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5.

Eng JW, Mace TA, Sharma R, Twum DYF, Peng P, Gibbs JF, Pitoniak R, Reed CB, Abrams SI, Repasky EA, Hylander BL. Eng JW, et al. Among authors: abrams si. J Immunother Cancer. 2016 Jun 21;4:33. doi: 10.1186/s40425-016-0136-y. eCollection 2016. J Immunother Cancer. 2016. PMID: 27330806 Free PMC article.

10

Relevance of Interferon Regulatory Factor-8 Expression in Myeloid-Tumor Interactions.

Abrams SI, Netherby CS, Twum DY, Messmer MN. Abrams SI, et al. J Interferon Cytokine Res. 2016 Jul;36(7):442-53. doi: 10.1089/jir.2015.0174. J Interferon Cytokine Res. 2016. PMID: 27379866 Free PMC article. Review.

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