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Gut enterochromaffin cells drive visceral pain and anxiety.
Bayrer JR, Castro J, Venkataraman A, Touhara KK, Rossen ND, Morrie RD, Maddern J, Hendry A, Braverman KN, Garcia-Caraballo S, Schober G, Brizuela M, Castro Navarro FM, Bueno-Silva C, Ingraham HA, Brierley SM, Julius D. Bayrer JR, et al. Among authors: brierley sm. Nature. 2023 Apr;616(7955):137-142. doi: 10.1038/s41586-023-05829-8. Epub 2023 Mar 22. Nature. 2023. PMID: 36949192 Free PMC article.
Selective role for TRPV4 ion channels in visceral sensory pathways.
Brierley SM, Page AJ, Hughes PA, Adam B, Liebregts T, Cooper NJ, Holtmann G, Liedtke W, Blackshaw LA. Brierley SM, et al. Gastroenterology. 2008 Jun;134(7):2059-69. doi: 10.1053/j.gastro.2008.01.074. Epub 2008 Jan 31. Gastroenterology. 2008. PMID: 18343379 Free PMC article.
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.
Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, Brierley SM, Basbaum AI, Bosmans F, King GF, Julius D. Osteen JD, et al. Among authors: brierley sm. Nature. 2016 Jun 23;534(7608):494-9. doi: 10.1038/nature17976. Epub 2016 Jun 6. Nature. 2016. PMID: 27281198 Free PMC article.
Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.
Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. Castro J, et al. Among authors: brierley sm. Br J Pharmacol. 2018 Jun;175(12):2384-2398. doi: 10.1111/bph.14115. Epub 2018 Feb 13. Br J Pharmacol. 2018. PMID: 29194563 Free PMC article.
Contribution of membrane receptor signalling to chronic visceral pain.
Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. Sadeghi M, et al. Among authors: brierley sm. Int J Biochem Cell Biol. 2018 May;98:10-23. doi: 10.1016/j.biocel.2018.02.017. Epub 2018 Mar 21. Int J Biochem Cell Biol. 2018. PMID: 29477359 Review.
109 results