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The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.
Antonschmidt L, Matthes D, Dervişoğlu R, Frieg B, Dienemann C, Leonov A, Nimerovsky E, Sant V, Ryazanov S, Giese A, Schröder GF, Becker S, de Groot BL, Griesinger C, Andreas LB. Antonschmidt L, et al. Among authors: dienemann c. Nat Commun. 2022 Sep 14;13(1):5385. doi: 10.1038/s41467-022-32797-w. Nat Commun. 2022. PMID: 36104315 Free PMC article.
Molecular interactions of FG nucleoporin repeats at high resolution.
Ibáñez de Opakua A, Geraets JA, Frieg B, Dienemann C, Savastano A, Rankovic M, Cima-Omori MS, Schröder GF, Zweckstetter M. Ibáñez de Opakua A, et al. Among authors: dienemann c. Nat Chem. 2022 Nov;14(11):1278-1285. doi: 10.1038/s41557-022-01035-7. Epub 2022 Sep 22. Nat Chem. 2022. PMID: 36138110 Free PMC article.
The 3D structure of lipidic fibrils of α-synuclein.
Frieg B, Antonschmidt L, Dienemann C, Geraets JA, Najbauer EE, Matthes D, de Groot BL, Andreas LB, Becker S, Griesinger C, Schröder GF. Frieg B, et al. Among authors: dienemann c. Nat Commun. 2022 Nov 10;13(1):6810. doi: 10.1038/s41467-022-34552-7. Nat Commun. 2022. PMID: 36357403 Free PMC article.
The structure of a dimeric form of SARS-CoV-2 polymerase.
Jochheim FA, Tegunov D, Hillen HS, Schmitzová J, Kokic G, Dienemann C, Cramer P. Jochheim FA, et al. Among authors: dienemann c. Commun Biol. 2021 Aug 24;4(1):999. doi: 10.1038/s42003-021-02529-9. Commun Biol. 2021. PMID: 34429502 Free PMC article.
Structure of an inactive RNA polymerase II dimer.
Aibara S, Dienemann C, Cramer P. Aibara S, et al. Among authors: dienemann c. Nucleic Acids Res. 2021 Oct 11;49(18):10747-10755. doi: 10.1093/nar/gkab783. Nucleic Acids Res. 2021. PMID: 34530439 Free PMC article.
46 results