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Venetoclax induces BCL-2-dependent Treg to TH17 plasticity to enhance the antitumor efficacy of anti-PD-1 checkpoint blockade.
Cancer Immunol Res. 2024 May 29. doi: 10.1158/2326-6066.CIR-23-0344. Online ahead of print.
Cancer Immunol Res. 2024.
PMID: 38810242
Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma.
Schnorenberg MR, Hawley KM, Thomas-Toth AT, Watkins EA, Tian Y, Ting JM, Leak LB, Kucera IM, Raczy MM, Kung AL, Hubbell JA, Tirrell MV, LaBelle JL.
Schnorenberg MR, et al. Among authors: thomas toth at.
ACS Nano. 2023 Dec 12;17(23):23374-23390. doi: 10.1021/acsnano.3c04112. Epub 2023 Sep 9.
ACS Nano. 2023.
PMID: 37688780
Free PMC article.
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Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.
Hawley KM, Eclov RJ, Schnorenberg MR, Tian Y, Shah RN, Thomas-Toth AT, Fefferman M, Bird GH, Walensky LD, Tirrell MV, LaBelle JL.
Hawley KM, et al. Among authors: thomas toth at.
Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2209044119. doi: 10.1073/pnas.2209044119. Epub 2022 Oct 13.
Proc Natl Acad Sci U S A. 2022.
PMID: 36227917
Free PMC article.
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Venetoclax imparts distinct cell death sensitivity and adaptivity patterns in T cells.
Ludwig LM, Hawley KM, Banks DB, Thomas-Toth AT, Blazar BR, McNerney ME, Leverson JD, LaBelle JL.
Ludwig LM, et al. Among authors: thomas toth at.
Cell Death Dis. 2021 Oct 27;12(11):1005. doi: 10.1038/s41419-021-04285-4.
Cell Death Dis. 2021.
PMID: 34707089
Free PMC article.
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