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Survival and Proliferation of Neural Progenitor-Derived Glioblastomas Under Hypoxic Stress is Controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism.
Calinescu AA, Yadav VN, Carballo E, Kadiyala P, Tran D, Zamler DB, Doherty R, Srikanth M, Lowenstein PR, Castro MG. Calinescu AA, et al. Among authors: doherty r. Clin Cancer Res. 2017 Mar 1;23(5):1250-1262. doi: 10.1158/1078-0432.CCR-15-2888. Epub 2016 Aug 19. Clin Cancer Res. 2017. PMID: 27542769 Free PMC article.
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery tool.
Wilson TJ, Zamler DB, Doherty R, Castro MG, Lowenstein PR. Wilson TJ, et al. Among authors: doherty r. Oncotarget. 2016 Sep 27;7(39):63020-63041. doi: 10.18632/oncotarget.11589. Oncotarget. 2016. PMID: 27564115 Free PMC article.
Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.
Koschmann C, Zamler D, MacKay A, Robinson D, Wu YM, Doherty R, Marini B, Tran D, Garton H, Muraszko K, Robertson P, Leonard M, Zhao L, Bixby D, Peterson L, Camelo-Piragua S, Jones C, Mody R, Lowenstein PR, Castro MG. Koschmann C, et al. Among authors: doherty r. Oncotarget. 2016 Oct 4;7(40):65696-65706. doi: 10.18632/oncotarget.11602. Oncotarget. 2016. PMID: 27582545 Free PMC article.
Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy.
Assi HH, Paran C, VanderVeen N, Savakus J, Doherty R, Petruzzella E, Hoeschele JD, Appelman H, Raptis L, Mikkelsen T, Lowenstein PR, Castro MG. Assi HH, et al. Among authors: doherty r. J Pharmacol Exp Ther. 2014 Jun;349(3):458-69. doi: 10.1124/jpet.114.214619. Epub 2014 Apr 2. J Pharmacol Exp Ther. 2014. PMID: 24696041 Free PMC article.
ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma.
Koschmann C, Calinescu AA, Nunez FJ, Mackay A, Fazal-Salom J, Thomas D, Mendez F, Kamran N, Dzaman M, Mulpuri L, Krasinkiewicz J, Doherty R, Lemons R, Brosnan-Cashman JA, Li Y, Roh S, Zhao L, Appelman H, Ferguson D, Gorbunova V, Meeker A, Jones C, Lowenstein PR, Castro MG. Koschmann C, et al. Among authors: doherty r. Sci Transl Med. 2016 Mar 2;8(328):328ra28. doi: 10.1126/scitranslmed.aac8228. Sci Transl Med. 2016. PMID: 26936505 Free PMC article.
589 results