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SOCS2 protects against chemical-induced hepatocellular carcinoma progression by modulating inflammation and cell proliferation in the liver.
Cabrera-Galván JJ, Araujo E, de Mirecki-Garrido M, Pérez-Rodríguez D, Guerra B, Aranda-Tavío H, Guerra-Rodríguez M, Brito-Casillas Y, Melián C, Martínez-Martín MS, Fernández-Pérez L, Recio C. Cabrera-Galván JJ, et al. Among authors: aranda tavio h. Biomed Pharmacother. 2023 Jan;157:114060. doi: 10.1016/j.biopha.2022.114060. Epub 2022 Nov 28. Biomed Pharmacother. 2023. PMID: 36455458 Free article.
Discovery of Highly Functionalized 5-hydroxy-2H-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen.
Guerra-Rodríguez M, López-Rojas P, Amesty Á, Aranda-Tavío H, Brito-Casillas Y, Estévez-Braun A, Fernández-Pérez L, Guerra B, Recio C. Guerra-Rodríguez M, et al. Among authors: aranda tavio h. Cancers (Basel). 2022 Oct 22;14(21):5174. doi: 10.3390/cancers14215174. Cancers (Basel). 2022. PMID: 36358593 Free PMC article.
JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.
Aranda-Tavío H, Recio C, Martín-Acosta P, Guerra-Rodríguez M, Brito-Casillas Y, Blanco R, Junco V, León J, Montero JC, Gandullo-Sánchez L, McNaughton-Smith G, Zapata JM, Pandiella A, Amesty A, Estévez-Braun A, Fernández-Pérez L, Guerra B. Aranda-Tavío H, et al. Biomed Pharmacother. 2021 Dec;144:112330. doi: 10.1016/j.biopha.2021.112330. Epub 2021 Oct 19. Biomed Pharmacother. 2021. PMID: 34673425 Free article.
The Mevalonate Pathway, a Metabolic Target in Cancer Therapy.
Guerra B, Recio C, Aranda-Tavío H, Guerra-Rodríguez M, García-Castellano JM, Fernández-Pérez L. Guerra B, et al. Among authors: aranda tavio h. Front Oncol. 2021 Feb 25;11:626971. doi: 10.3389/fonc.2021.626971. eCollection 2021. Front Oncol. 2021. PMID: 33718197 Free PMC article. Review.
Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation.
Purvis GSD, Collino M, Aranda-Tavio H, Chiazza F, O'Riordan CE, Zeboudj L, Mohammad S, Collotta D, Verta R, Guisot NES, Bunyard P, Yaqoob MM, Greaves DR, Thiemermann C. Purvis GSD, et al. Among authors: aranda tavio h. Br J Pharmacol. 2020 Oct;177(19):4416-4432. doi: 10.1111/bph.15182. Epub 2020 Aug 26. Br J Pharmacol. 2020. PMID: 32608058 Free PMC article.
Signal transducer and activator of transcription (STAT)-5: an opportunity for drug development in oncohematology.
Recio C, Guerra B, Guerra-Rodríguez M, Aranda-Tavío H, Martín-Rodríguez P, de Mirecki-Garrido M, Brito-Casillas Y, García-Castellano JM, Estévez-Braun A, Fernández-Pérez L. Recio C, et al. Among authors: aranda tavio h. Oncogene. 2019 Jun;38(24):4657-4668. doi: 10.1038/s41388-019-0752-3. Epub 2019 Feb 19. Oncogene. 2019. PMID: 30783189 Review.
A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells.
Martín-Rodríguez P, Guerra B, Hueso-Falcón I, Aranda-Tavío H, Díaz-Chico J, Quintana J, Estévez F, Díaz-Chico B, Amesty A, Estévez-Braun A, Fernández-Pérez L. Martín-Rodríguez P, et al. Among authors: aranda tavio h. Front Pharmacol. 2019 Jan 9;9:1546. doi: 10.3389/fphar.2018.01546. eCollection 2018. Front Pharmacol. 2019. PMID: 30687103 Free PMC article.