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Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration.
Ryan SK, Zelic M, Han Y, Teeple E, Chen L, Sadeghi M, Shankara S, Guo L, Li C, Pontarelli F, Jensen EH, Comer AL, Kumar D, Zhang M, Gans J, Zhang B, Proto JD, Saleh J, Dodge JC, Savova V, Rajpal D, Ofengeim D, Hammond TR. Ryan SK, et al. Among authors: gans j. Nat Neurosci. 2023 Jan;26(1):12-26. doi: 10.1038/s41593-022-01221-3. Epub 2022 Dec 19. Nat Neurosci. 2023. PMID: 36536241 Free PMC article.
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation.
Jafari M, Schumacher AM, Snaidero N, Ullrich Gavilanes EM, Neziraj T, Kocsis-Jutka V, Engels D, Jürgens T, Wagner I, Weidinger JDF, Schmidt SS, Beltrán E, Hagan N, Woodworth L, Ofengeim D, Gans J, Wolf F, Kreutzfeldt M, Portugues R, Merkler D, Misgeld T, Kerschensteiner M. Jafari M, et al. Among authors: gans j. Nat Neurosci. 2021 Mar;24(3):355-367. doi: 10.1038/s41593-020-00780-7. Epub 2021 Jan 25. Nat Neurosci. 2021. PMID: 33495636
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy.
Boddupalli CS, Nair S, Belinsky G, Gans J, Teeple E, Nguyen TH, Mehta S, Guo L, Kramer ML, Ruan J, Wang H, Davison M, Kumar D, Vidyadhara DJ, Zhang B, Klinger K, Mistry PK. Boddupalli CS, et al. Among authors: gans j. Elife. 2022 Aug 16;11:e79830. doi: 10.7554/eLife.79830. Elife. 2022. PMID: 35972072 Free PMC article.
Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence.
Byrne A, McLaren RP, Mason P, Chai L, Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, Gladysheva TB, Teicher BA, Biemann HP, Booker M, Goldberg MA, Klinger KW, Lillie J, Madden SL, Jiang Y. Byrne A, et al. Among authors: gans jd. Exp Cell Res. 2010 Jan 15;316(2):258-71. doi: 10.1016/j.yexcr.2009.08.018. Epub 2009 Sep 2. Exp Cell Res. 2010. PMID: 19732767
Do we want less automation?
Agrawal A, Gans JS, Goldfarb A. Agrawal A, et al. Among authors: gans js. Science. 2023 Jul 14;381(6654):155-158. doi: 10.1126/science.adh9429. Epub 2023 Jul 13. Science. 2023. PMID: 37440634
322 results