Fry AM - Search Results

1

BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms.

Singh A, Busacca S, Gaba A, Sheaff M, Poile C, Nakas A, Dzialo J, Bzura A, Dawson AG, Fennell DA, Fry AM. Singh A, et al. Among authors: fry am. Oncogene. 2023 Feb;42(8):572-585. doi: 10.1038/s41388-022-02577-3. Epub 2022 Dec 22. Oncogene. 2023. PMID: 36550359 Free PMC article.

2

BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma.

Busacca S, O'Regan L, Singh A, Sharkey AJ, Dawson AG, Dzialo J, Parsons A, Kumar N, Schunselaar LM, Guppy N, Nakas A, Sheaff M, Mansfield AS, Janes SM, Baas P, Fry AM, Fennell DA. Busacca S, et al. Among authors: fry am. Mol Cancer Ther. 2021 Feb;20(2):379-388. doi: 10.1158/1535-7163.MCT-20-0363. Epub 2020 Nov 6. Mol Cancer Ther. 2021. PMID: 33158996

3

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain.

Richards MW, Law EW, Rennalls LP, Busacca S, O'Regan L, Fry AM, Fennell DA, Bayliss R. Richards MW, et al. Among authors: fry am. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5195-200. doi: 10.1073/pnas.1322892111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706829 Free PMC article.

4

Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs.

Bayliss R, Choi J, Fennell DA, Fry AM, Richards MW. Bayliss R, et al. Among authors: fry am. Cell Mol Life Sci. 2016 Mar;73(6):1209-24. doi: 10.1007/s00018-015-2117-6. Epub 2016 Jan 11. Cell Mol Life Sci. 2016. PMID: 26755435 Free PMC article. Review.

5

EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7.

O'Regan L, Barone G, Adib R, Woo CG, Jeong HJ, Richardson EL, Richards MW, Muller PAJ, Collis SJ, Fennell DA, Choi J, Bayliss R, Fry AM. O'Regan L, et al. Among authors: fry am. J Cell Sci. 2020 May 11;133(9):jcs241505. doi: 10.1242/jcs.241505. J Cell Sci. 2020. PMID: 32184261 Free PMC article.

6

[No title available]

[No authors listed] [No authors listed] PMID: 34005150

7

The Nek2 protein kinase: a novel regulator of centrosome structure.

Fry AM. Fry AM. Oncogene. 2002 Sep 9;21(40):6184-94. doi: 10.1038/sj.onc.1205711. Oncogene. 2002. PMID: 12214248 Review.

8

EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity.

Lucken K, O'Regan L, Choi J, Sampson J, Pashley SL, Bayliss R, Khan S, Fry AM. Lucken K, et al. Among authors: fry am. Mol Cancer Res. 2022 Jun 3;20(6):854-866. doi: 10.1158/1541-7786.MCR-21-1010. Mol Cancer Res. 2022. PMID: 35656694 Free PMC article.

9

Mitotic regulation by NIMA-related kinases.

O'regan L, Blot J, Fry AM. O'regan L, et al. Among authors: fry am. Cell Div. 2007 Aug 29;2:25. doi: 10.1186/1747-1028-2-25. Cell Div. 2007. PMID: 17727698 Free PMC article.

10

On the molecular mechanisms of mitotic kinase activation.

Bayliss R, Fry A, Haq T, Yeoh S. Bayliss R, et al. Open Biol. 2012 Nov;2(11):120136. doi: 10.1098/rsob.120136. Open Biol. 2012. PMID: 23226601 Free PMC article. Review.

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