Mulcrone PL - Search Results

1

Cryptic resolution sites in the vector plasmid lead to the heterogeneities in the rAAV vectors.

Zhang J, Chrzanowski M, Frabutt DA, Lam AK, Mulcrone PL, Li L, Konkle BA, Miao CH, Xiao W. Zhang J, et al. Among authors: mulcrone pl. J Med Virol. 2023 Jan;95(1):e28433. doi: 10.1002/jmv.28433. J Med Virol. 2023. PMID: 36571262 Free PMC article.

2

Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS.

Lam AK, Zhang J, Frabutt D, Mulcrone PL, Li L, Zeng L, Herzog RW, Xiao W. Lam AK, et al. Among authors: mulcrone pl. Mol Ther Methods Clin Dev. 2022 Sep 24;27:185-194. doi: 10.1016/j.omtm.2022.09.008. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36284765 Free PMC article.

3

Adding recombinant AAVs to the cancer therapeutics mix.

Mulcrone PL, Herzog RW, Xiao W. Mulcrone PL, et al. Mol Ther Oncolytics. 2022 Oct 2;27:73-88. doi: 10.1016/j.omto.2022.09.009. eCollection 2022 Dec 15. Mol Ther Oncolytics. 2022. PMID: 36321134 Free PMC article. Review.

4

Genomic Designs of rAAVs Contribute to Pathological Changes in the Livers and Spleens of Mice.

Mulcrone PL, Zhang J, Pride PM, Lam AK, Frabutt DA, Ball-Kell SM, Xiao W. Mulcrone PL, et al. Adv Cell Gene Ther. 2022;2022:6807904. doi: 10.1155/2022/6807904. Epub 2022 Mar 20. Adv Cell Gene Ther. 2022. PMID: 36507314 Free PMC article.

5

Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism.

Mulcrone PL, Lam AK, Frabutt D, Zhang J, Chrzanowski M, Herzog RW, Xiao W. Mulcrone PL, et al. Sci Rep. 2023 May 25;13(1):8436. doi: 10.1038/s41598-023-35547-0. Sci Rep. 2023. PMID: 37231038 Free PMC article.

6

A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR.

Zhang J, Frabutt DA, Chrzanowski M, Li N, Miller LM, Tian J, Mulcrone PL, Lam AK, Draper BE, Jarrold MF, Herzog RW, Xiao W. Zhang J, et al. Among authors: mulcrone pl. Mol Ther Methods Clin Dev. 2024 Feb 3;32(1):101206. doi: 10.1016/j.omtm.2024.101206. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38390555 Free PMC article.

7

Comprehensive Comparison of AAV Purification Methods: Iodixanol Gradient Centrifugation vs. Immuno-Affinity Chromatography.

Lam AK, Mulcrone PL, Frabutt D, Zhang J, Chrzanowski M, Arisa S, Munoz M, Li X, Biswas M, Markusic D, Herzog RW, Xiao W. Lam AK, et al. Among authors: mulcrone pl. Adv Cell Gene Ther. 2023;2023:2339702. doi: 10.1155/2023/2339702. Epub 2023 Dec 11. Adv Cell Gene Ther. 2023. PMID: 38130431 Free PMC article.

8

Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation.

Miyagawa K, Tenshin H, Mulcrone PL, Delgado-Calle J, Subler MA, Windle JJ, Chirgwin JM, Roodman GD, Kurihara N. Miyagawa K, et al. Among authors: mulcrone pl. JCI Insight. 2023 Jul 24;8(14):e159838. doi: 10.1172/jci.insight.159838. JCI Insight. 2023. PMID: 37338990 Free PMC article.

9

Subgenomic particles in rAAV vectors result from DNA lesion/break and non-homologous end joining of vector genomes.

Zhang J, Guo P, Yu X, Frabutt DA, Lam AK, Mulcrone PL, Chrzanowski M, Firrman J, Pouchnik D, Sang N, Diao Y, Herzog RW, Xiao W. Zhang J, et al. Among authors: mulcrone pl. Mol Ther Nucleic Acids. 2022 Aug 24;29:852-861. doi: 10.1016/j.omtn.2022.08.027. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 36159586 Free PMC article.

10

GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival.

Petrusca DN, Mulcrone PL, Macar DA, Bishop RT, Berdyshev E, Suvannasankha A, Anderson JL, Sun Q, Auron PE, Galson DL, Roodman GD. Petrusca DN, et al. Among authors: mulcrone pl. Cancers (Basel). 2022 Feb 2;14(3):772. doi: 10.3390/cancers14030772. Cancers (Basel). 2022. PMID: 35159039 Free PMC article.

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