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Clocking cancer: the circadian clock as a target in cancer therapy.
Battaglin F, Chan P, Pan Y, Soni S, Qu M, Spiller ER, Castanon S, Roussos Torres ET, Mumenthaler SM, Kay SA, Lenz HJ. Battaglin F, et al. Among authors: lenz hj. Oncogene. 2021 May;40(18):3187-3200. doi: 10.1038/s41388-021-01778-6. Epub 2021 Apr 12. Oncogene. 2021. PMID: 33846572 Free PMC article. Review.
IL-33 activates tumor stroma to promote intestinal polyposis.
Maywald RL, Doerner SK, Pastorelli L, De Salvo C, Benton SM, Dawson EP, Lanza DG, Berger NA, Markowitz SD, Lenz HJ, Nadeau JH, Pizarro TT, Heaney JD. Maywald RL, et al. Among authors: lenz hj. Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2487-96. doi: 10.1073/pnas.1422445112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918379 Free PMC article.
A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma.
El-Khoueiry AB, O'Donnell R, Semrad TJ, Mack P, Blanchard S, Bahary N, Jiang Y, Yen Y, Wright J, Chen H, Lenz HJ, Gandara DR. El-Khoueiry AB, et al. Among authors: lenz hj. Cancer Chemother Pharmacol. 2018 May;81(5):957-963. doi: 10.1007/s00280-018-3553-4. Epub 2018 Mar 8. Cancer Chemother Pharmacol. 2018. PMID: 29520435 Free PMC article. Clinical Trial.
Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A.
Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, Betge J, Härtel N, Kather JN, Weis CA, Gaiser T, Marx A, Weiss C, Hofheinz R, Miller IS, Loupakis F, Lenz HJ, Byrne AT, Ebert MP. Burgermeister E, et al. Among authors: lenz hj. EBioMedicine. 2019 Jul;45:139-154. doi: 10.1016/j.ebiom.2019.07.004. Epub 2019 Jul 9. EBioMedicine. 2019. PMID: 31300350 Free PMC article.
683 results