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Synthesis of Triphenylphosphonium-Linked Derivative of 3,5-Ditert-butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler.
ACS Omega. 2024 Feb 29;9(10):11551-11561. doi: 10.1021/acsomega.3c08621. eCollection 2024 Mar 12.
ACS Omega. 2024.
PMID: 38496966
Free PMC article.
Ester-stabilized phosphorus ylides as protonophores on bilayer lipid membranes, mitochondria and chloroplasts.
Kirsanov RS, Khailova LS, Rokitskaya TI, Iaubasarova IR, Nazarov PA, Panteleeva AA, Lyamzaev KG, Popova LB, Korshunova GA, Kotova EA, Antonenko YN.
Kirsanov RS, et al. Among authors: iaubasarova ir.
Bioelectrochemistry. 2023 Apr;150:108369. doi: 10.1016/j.bioelechem.2023.108369. Epub 2023 Jan 5.
Bioelectrochemistry. 2023.
PMID: 36638678
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Linking 7-Nitrobenzo-2-oxa-1,3-diazole (NBD) to Triphenylphosphonium Yields Mitochondria-Targeted Protonophore and Antibacterial Agent.
Iaubasarova IR, Khailova LS, Nazarov PA, Rokitskaya TI, Silachev DN, Danilina TI, Plotnikov EY, Denisov SS, Kirsanov RS, Korshunova GA, Kotova EA, Zorov DB, Antonenko YN.
Iaubasarova IR, et al.
Biochemistry (Mosc). 2020 Dec;85(12):1578-1590. doi: 10.1134/S000629792012010X.
Biochemistry (Mosc). 2020.
PMID: 33705296
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The mitochondria-targeted derivative of the classical uncoupler of oxidative phosphorylation carbonyl cyanide m-chlorophenylhydrazone is an effective mitochondrial recoupler.
Iaubasarova IR, Khailova LS, Firsov AM, Grivennikova VG, Kirsanov RS, Korshunova GA, Kotova EA, Antonenko YN.
Iaubasarova IR, et al.
PLoS One. 2020 Dec 30;15(12):e0244499. doi: 10.1371/journal.pone.0244499. eCollection 2020.
PLoS One. 2020.
PMID: 33378414
Free PMC article.
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