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Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation.
Sanchez A, Adam C, Rauh F, Duroc Y, Ranjha L, Lombard B, Mu X, Wintrebert M, Loew D, Guarné A, Gnan S, Chen CL, Keeney S, Cejka P, Guérois R, Klein F, Charbonnier JB, Borde V. Sanchez A, et al. Among authors: chen cl. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30577-30588. doi: 10.1073/pnas.2013012117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199619 Free PMC article.
Kronos scRT: a uniform framework for single-cell replication timing analysis.
Gnan S, Josephides JM, Wu X, Spagnuolo M, Saulebekova D, Bohec M, Dumont M, Baudrin LG, Fachinetti D, Baulande S, Chen CL. Gnan S, et al. Among authors: chen cl. Nat Commun. 2022 Apr 28;13(1):2329. doi: 10.1038/s41467-022-30043-x. Nat Commun. 2022. PMID: 35484127 Free PMC article.
Editorial: DNA Replication Stress and Cell Fate.
Deng L, Chen CL, Zhai Y, Dong Y, Lou H. Deng L, et al. Among authors: chen cl. Front Cell Dev Biol. 2021 Oct 25;9:778486. doi: 10.3389/fcell.2021.778486. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34760895 Free PMC article. No abstract available.
Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome.
Chakraborty A, Jenjaroenpun P, Li J, El Hilali S, McCulley A, Haarer B, Hoffman EA, Belak A, Thorland A, Hehnly H, Schildkraut CL, Chen CL, Kuznetsov VA, Feng W. Chakraborty A, et al. Among authors: chen cl. Cell Rep. 2020 Sep 22;32(12):108179. doi: 10.1016/j.celrep.2020.108179. Cell Rep. 2020. PMID: 32966779 Free PMC article.
OKseqHMM: a genome-wide replication fork directionality analysis toolkit.
Liu Y, Wu X, d'Aubenton-Carafa Y, Thermes C, Chen CL. Liu Y, et al. Among authors: chen cl. Nucleic Acids Res. 2023 Feb 28;51(4):e22. doi: 10.1093/nar/gkac1239. Nucleic Acids Res. 2023. PMID: 36629249 Free PMC article.
To study the direction of replication fork movement and TRCs, we developed a bioinformatics toolkit called OKseqHMM (https://github.com/CL-CHEN-Lab/OK-Seq, https://doi.org/10.5281/zenodo.7428883). Then, we used OKseqHMM to analyse a large number of datasets obtained …
To study the direction of replication fork movement and TRCs, we developed a bioinformatics toolkit called OKseqHMM (https://github.com/C …
4,454 results