Ko C - Search Results

1

Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure.

Allweiss L, Testoni B, Yu M, Lucifora J, Ko C, Qu B, Lütgehetmann M, Guo H, Urban S, Fletcher SP, Protzer U, Levrero M, Zoulim F, Dandri M. Allweiss L, et al. Among authors: ko c. Gut. 2023 May;72(5):972-983. doi: 10.1136/gutjnl-2022-328380. Epub 2023 Jan 27. Gut. 2023. PMID: 36707234 Free PMC article.

2

Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA.

Michler T, Große S, Mockenhaupt S, Röder N, Stückler F, Knapp B, Ko C, Heikenwalder M, Protzer U, Grimm D. Michler T, et al. Among authors: ko c. EMBO Mol Med. 2016 Sep 1;8(9):1082-98. doi: 10.15252/emmm.201506172. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27473329 Free PMC article.

3

Analyses of HBV cccDNA Quantification and Modification.

Xia Y, Stadler D, Ko C, Protzer U. Xia Y, et al. Among authors: ko c. Methods Mol Biol. 2017;1540:59-72. doi: 10.1007/978-1-4939-6700-1_6. Methods Mol Biol. 2017. PMID: 27975308

4

Novel viral and host targets to cure hepatitis B.

Ko C, Michler T, Protzer U. Ko C, et al. Curr Opin Virol. 2017 Jun;24:38-45. doi: 10.1016/j.coviro.2017.03.019. Epub 2017 Apr 20. Curr Opin Virol. 2017. PMID: 28433762 Review.

5

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.

Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: ko c. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.

6

Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels.

Ko C, Chakraborty A, Chou WM, Hasreiter J, Wettengel JM, Stadler D, Bester R, Asen T, Zhang K, Wisskirchen K, McKeating JA, Ryu WS, Protzer U. Ko C, et al. J Hepatol. 2018 Dec;69(6):1231-1241. doi: 10.1016/j.jhep.2018.08.012. Epub 2018 Aug 22. J Hepatol. 2018. PMID: 30142426 Free PMC article.

7

Hepatitis B virus promotes β-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion.

von Olshausen G, Quasdorff M, Bester R, Arzberger S, Ko C, van de Klundert M, Zhang K, Odenthal M, Ringelhan M, Niessen CM, Protzer U. von Olshausen G, et al. Among authors: ko c. Oncotarget. 2018 Sep 21;9(74):33947-33960. doi: 10.18632/oncotarget.26103. eCollection 2018 Sep 21. Oncotarget. 2018. PMID: 30338037 Free PMC article.

8

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.

Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA. Wing PA, et al. Among authors: ko c. Life Sci Alliance. 2019 Mar 27;2(2):e201900355. doi: 10.26508/lsa.201900355. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30918010 Free PMC article.

9

Comparative Analysis of the Antiviral Effects Mediated by Type I and III Interferons in Hepatitis B Virus-Infected Hepatocytes.

Bockmann JH, Stadler D, Xia Y, Ko C, Wettengel JM, Schulze Zur Wiesch J, Dandri M, Protzer U. Bockmann JH, et al. Among authors: ko c. J Infect Dis. 2019 Jul 19;220(4):567-577. doi: 10.1093/infdis/jiz143. J Infect Dis. 2019. PMID: 30923817

10

A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection.

Ko C, Bester R, Zhou X, Xu Z, Blossey C, Sacherl J, Vondran FWR, Gao L, Protzer U. Ko C, et al. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01440-19. doi: 10.1128/AAC.01440-19. Print 2019 Dec 20. Antimicrob Agents Chemother. 2019. PMID: 31658963 Free PMC article.

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