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Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans.
Vylegzhanina AV, Bespalov IA, Novototskaya-Vlasova KA, Hall BM, Gleiberman AS, Yu H, Leontieva OV, Leonova KI, Kurnasov OV, Osterman AL, Dy GK, Komissarov AA, Vasilieva E, Gehlhausen J, Iwasaki A, Ambrosone CB, Tsuji T, Matsuzaki J, Odunsi K, Andrianova EL, Gudkov AV. Vylegzhanina AV, et al. Among authors: leonova ki. Cancer Res Commun. 2023 Nov 8;3(11):2256-2267. doi: 10.1158/2767-9764.CRC-23-0289. Cancer Res Commun. 2023. PMID: 37870410 Free PMC article.
Comparison of cell response to chromatin and DNA damage.
Luzhin A, Rajan P, Safina A, Leonova K, Stablewski A, Wang J, Robinson D, Isaeva N, Kantidze O, Gurova K. Luzhin A, et al. Among authors: leonova k. Nucleic Acids Res. 2023 Nov 27;51(21):11836-11855. doi: 10.1093/nar/gkad865. Nucleic Acids Res. 2023. PMID: 37855682 Free PMC article.
Comparison of cell response to chromatin and DNA damage.
Luzhin A, Rajan P, Safina A, Leonova K, Stablewski A, Wang J, Pal M, Kantidze O, Gurova K. Luzhin A, et al. Among authors: leonova k. bioRxiv [Preprint]. 2023 Jan 18:2023.01.17.524424. doi: 10.1101/2023.01.17.524424. bioRxiv. 2023. PMID: 36711582 Free PMC article. Updated. Preprint.
Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors.
Novototskaya-Vlasova KA, Neznanov NS, Molodtsov I, Hall BM, Commane M, Gleiberman AS, Murray J, Haber M, Norris MD, Leonova KI, Gudkov AV. Novototskaya-Vlasova KA, et al. Among authors: leonova ki. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2213146119. doi: 10.1073/pnas.2213146119. Epub 2022 Nov 30. Proc Natl Acad Sci U S A. 2022. PMID: 36449545 Free PMC article.
Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Xiao L, Somers K, Murray J, Pandher R, Karsa M, Ronca E, Bongers A, Terry R, Ehteda A, Gamble LD, Issaeva N, Leonova KI, O'Connor A, Mayoh C, Venkat P, Quek H, Brand J, Kusuma FK, Pettitt JA, Mosmann E, Kearns A, Eden G, Alfred S, Allan S, Zhai L, Kamili A, Gifford AJ, Carter DR, Henderson MJ, Fletcher JI, Marshall G, Johnstone RW, Cesare AJ, Ziegler DS, Gudkov AV, Gurova KV, Norris MD, Haber M. Xiao L, et al. Among authors: leonova ki. Clin Cancer Res. 2021 Aug 1;27(15):4338-4352. doi: 10.1158/1078-0432.CCR-20-2357. Epub 2021 May 16. Clin Cancer Res. 2021. PMID: 33994371 Free PMC article.
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V. Simon M, et al. Among authors: leonova ki. Cell Metab. 2019 Apr 2;29(4):871-885.e5. doi: 10.1016/j.cmet.2019.02.014. Epub 2019 Mar 7. Cell Metab. 2019. PMID: 30853213 Free PMC article.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: leonova ki. J Clin Invest. 2018 Oct 1;128(10):4682-4696. doi: 10.1172/JCI70712. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198908 Free PMC article.
p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli.
Hall BM, Balan V, Gleiberman AS, Strom E, Krasnov P, Virtuoso LP, Rydkina E, Vujcic S, Balan K, Gitlin II, Leonova KI, Consiglio CR, Gollnick SO, Chernova OB, Gudkov AV. Hall BM, et al. Among authors: leonova ki. Aging (Albany NY). 2017 Aug 2;9(8):1867-1884. doi: 10.18632/aging.101268. Aging (Albany NY). 2017. PMID: 28768895 Free PMC article.
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