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Page 1
Gene expression signature predicts rate of type 1 diabetes progression.
Suomi T, Starskaia I, Kalim UU, Rasool O, Jaakkola MK, Grönroos T, Välikangas T, Brorsson C, Mazzoni G, Bruggraber S, Overbergh L, Dunger D, Peakman M, Chmura P, Brunak S, Schulte AM, Mathieu C, Knip M, Lahesmaa R, Elo LL; INNODIA Consortium. Suomi T, et al. EBioMedicine. 2023 Jun;92:104625. doi: 10.1016/j.ebiom.2023.104625. Epub 2023 May 22. EBioMedicine. 2023. PMID: 37224769 Free PMC article.
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Among authors: otonkoski t. Protein Sci. 2024 Apr;33(4):e4949. doi: 10.1002/pro.4949. Protein Sci. 2024. PMID: 38511500 Free PMC article.
Comprehensive characterization of the embryonic factor LEUTX.
Gawriyski L, Jouhilahti EM, Yoshihara M, Fei L, Weltner J, Airenne TT, Trokovic R, Bhagat S, Tervaniemi MH, Murakawa Y, Salokas K, Liu X, Miettinen S, Bürglin TR, Sahu B, Otonkoski T, Johnson MS, Katayama S, Varjosalo M, Kere J. Gawriyski L, et al. Among authors: otonkoski t. iScience. 2023 Feb 9;26(3):106172. doi: 10.1016/j.isci.2023.106172. eCollection 2023 Mar 17. iScience. 2023. PMID: 36876139 Free PMC article.
Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders.
Auvinen P, Vehviläinen J, Marjonen H, Modhukur V, Sokka J, Wallén E, Rämö K, Ahola L, Salumets A, Otonkoski T, Skottman H, Ollikainen M, Trokovic R, Kahila H, Kaminen-Ahola N. Auvinen P, et al. Among authors: otonkoski t. BMC Med. 2022 Dec 30;20(1):495. doi: 10.1186/s12916-022-02699-1. BMC Med. 2022. PMID: 36581877 Free PMC article.
A splice site variant in MADD affects hormone expression in pancreatic β cells and pituitary gonadotropes.
Pulli K, Saarimäki-Vire J, Ahonen P, Liu X, Ibrahim H, Chandra V, Santambrogio A, Wang Y, Vaaralahti K, Iivonen AP, Känsäkoski J, Tommiska J, Kemkem Y, Varjosalo M, Vuoristo S, Andoniadou CL, Otonkoski T, Raivio T. Pulli K, et al. Among authors: otonkoski t. JCI Insight. 2024 May 22;9(10):e167598. doi: 10.1172/jci.insight.167598. JCI Insight. 2024. PMID: 38775154 Free article.
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function.
Ibrahim H, Balboa D, Saarimäki-Vire J, Montaser H, Dyachok O, Lund PE, Omar-Hmeadi M, Kvist J, Dwivedi OP, Lithovius V, Barsby T, Chandra V, Eurola S, Ustinov J, Tuomi T, Miettinen PJ, Barg S, Tengholm A, Otonkoski T. Ibrahim H, et al. Among authors: otonkoski t. Diabetologia. 2024 May 14. doi: 10.1007/s00125-024-06163-y. Online ahead of print. Diabetologia. 2024. PMID: 38743124
Efficient vascular and neural engraftment of stem cell-derived islets.
Thorngren J, Brboric A, Vasylovska S, Hjelmqvist D, Westermark GT, Saarimäki-Vire J, Kvist J, Balboa D, Otonkoski T, Carlsson PO, Lau J. Thorngren J, et al. Among authors: otonkoski t. Diabetes. 2024 Apr 11:db230123. doi: 10.2337/db23-0123. Online ahead of print. Diabetes. 2024. PMID: 38603470
217 results