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261 results

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Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial.
Qu JZ, Mueller A, McKay TB, Westover MB, Shelton KT, Shaefi S, D'Alessandro DA, Berra L, Brown EN, Houle TT, Akeju O; MINDDS Study Team. Qu JZ, et al. Among authors: houle tt. EClinicalMedicine. 2022 Dec 24;56:101796. doi: 10.1016/j.eclinm.2022.101796. eCollection 2023 Feb. EClinicalMedicine. 2022. PMID: 36590787 Free PMC article.
Age-Dependent Electroencephalogram Features in Infants Under Spinal Anesthesia Appear to Mirror Physiologic Sleep in the Developing Brain: A Prospective Observational Study.
Santa Cruz Mercado LA, Lee JM, Liu R, Deng H, Johnson JJ, Chen AL, He M, Chung ER, Bharadwaj KM, Houle TT, Purdon PL, Liu CA. Santa Cruz Mercado LA, et al. Among authors: houle tt. Anesth Analg. 2023 Dec 1;137(6):1241-1249. doi: 10.1213/ANE.0000000000006410. Epub 2023 Mar 7. Anesth Analg. 2023. PMID: 36881544
The association between gut microbiota and postoperative delirium in patients.
Zhang Y, Baldyga K, Dong Y, Song W, Villanueva M, Deng H, Mueller A, Houle TT, Marcantonio ER, Xie Z. Zhang Y, et al. Among authors: houle tt. Transl Psychiatry. 2023 May 9;13(1):156. doi: 10.1038/s41398-023-02450-1. Transl Psychiatry. 2023. PMID: 37160886 Free PMC article. Review.
Indole-3-Propionic Acid, a Gut Microbiota Metabolite, Protects Against the Development of Postoperative Delirium.
Zhou X, Wu X, Wu Y, Yang L, Shi E, Ding W, Chen L, Shi X, Feng X, Su C, You Z, Xia J, Chen C, Yeliseyev V, Bry L, Xia S, Huang P, Meng J, Houle T, Akeju O, Mao J, Gerszten R, Chen Q, Xie Z, Shen S. Zhou X, et al. Among authors: houle t. Ann Surg. 2023 Dec 1;278(6):e1164-e1174. doi: 10.1097/SLA.0000000000005886. Epub 2023 Apr 27. Ann Surg. 2023. PMID: 37185230 Free PMC article.
Association Between Postoperative Delirium and Long-Term Subjective Cognitive Decline in Older Patients Undergoing Cardiac Surgery: A Secondary Analysis of the Minimizing Intensive Care Unit Neurological Dysfunction with Dexmedetomidine-Induced Sleep Trial.
Namirembe GE, Baker S, Albanese M, Mueller A, Qu JZ, Mekonnen J, Wiredu K, Westover MB, Houle TT, Akeju O; Minimizing Intensive Care Unit Neurological Dysfunction with Dexmedetomidine-Induced Sleep Study Team. Namirembe GE, et al. Among authors: houle tt. J Cardiothorac Vasc Anesth. 2023 Sep;37(9):1700-1706. doi: 10.1053/j.jvca.2023.04.035. Epub 2023 Apr 30. J Cardiothorac Vasc Anesth. 2023. PMID: 37217424 Clinical Trial.
Association of Intraoperative Opioid Administration With Postoperative Pain and Opioid Use.
Santa Cruz Mercado LA, Liu R, Bharadwaj KM, Johnson JJ, Gutierrez R, Das P, Balanza G, Deng H, Pandit A, Stone TAD, Macdonald T, Horgan C, Tou SLJ, Houle TT, Bittner EA, Purdon PL. Santa Cruz Mercado LA, et al. Among authors: houle tt. JAMA Surg. 2023 Aug 1;158(8):854-864. doi: 10.1001/jamasurg.2023.2009. JAMA Surg. 2023. PMID: 37314800 Free PMC article.
High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure Due to COVID-19: A Multicenter Phase II Trial.
Di Fenza R, Shetty NS, Gianni S, Parcha V, Giammatteo V, Safaee Fakhr B, Tornberg D, Wall O, Harbut P, Lai PS, Li JZ, Paganoni S, Cenci S, Mueller AL, Houle TT, Akeju O, Bittner EA, Bose S, Scott LK, Carroll RW, Ichinose F, Hedenstierna M, Arora P, Berra L; Nitric Oxide Investigators. Di Fenza R, et al. Among authors: houle tt. Am J Respir Crit Care Med. 2023 Dec 15;208(12):1293-1304. doi: 10.1164/rccm.202304-0637OC. Am J Respir Crit Care Med. 2023. PMID: 37774011 Free PMC article. Clinical Trial.
261 results