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Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension.
Tanabe N, Ikeda S, Tahara N, Fukuda K, Hatano M, Ito H, Nakayama T, Anzai T, Hashimoto A, Inoue T, Kajinami K, Kihara Y, Kinoshita H, Kuwahara K, Murohara T, Okazaki O, Sakai S, Satoh T, Takeda Y, Takeishi Y, Taniguchi M, Watanabe H, Yamamoto T, Yamauchi-Takihara K, Yoshioka K, Sasayama S. Tanabe N, et al. Among authors: kinoshita h. Circ J. 2017 Aug 25;81(9):1360-1367. doi: 10.1253/circj.CJ-16-1348. Epub 2017 Apr 18. Circ J. 2017. PMID: 28420826 Free article. Clinical Trial.
Selexipag for the treatment of chronic thromboembolic pulmonary hypertension.
Ogo T, Shimokawahara H, Kinoshita H, Sakao S, Abe K, Matoba S, Motoki H, Takama N, Ako J, Ikeda Y, Joho S, Maki H, Saeki T, Sugano T, Tsujino I, Yoshioka K, Shiota N, Tanaka S, Yamamoto C, Tanabe N, Tatsumi K; Study Group. Ogo T, et al. Among authors: kinoshita h. Eur Respir J. 2022 Jul 7;60(1):2101694. doi: 10.1183/13993003.01694-2021. Print 2022 Jul. Eur Respir J. 2022. PMID: 34824052 Free PMC article. Clinical Trial.
Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice.
Kobayashi H, Kabata R, Kinoshita H, Morimoto T, Ono K, Takeda M, Choi J, Okuda H, Liu W, Harada KH, Kimura T, Youssefian S, Koizumi A. Kobayashi H, et al. Among authors: kinoshita h. Pulm Circ. 2018 Jul-Sep;8(3):2045894018778155. doi: 10.1177/2045894018778155. Epub 2018 May 2. Pulm Circ. 2018. PMID: 29718794 Free PMC article.
Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction.
Kawakami R, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Nakagawa Y, Nakanishi M, Tanimoto K, Usami S, Yasuno S, Kinoshita H, Chusho H, Tamura N, Ogawa Y, Nakao K. Kawakami R, et al. Among authors: kinoshita h. Circulation. 2004 Nov 23;110(21):3306-12. doi: 10.1161/01.CIR.0000147829.78357.C5. Epub 2004 Nov 15. Circulation. 2004. PMID: 15545516
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
Kinoshita H, Kuwahara K, Takano M, Arai Y, Kuwabara Y, Yasuno S, Nakagawa Y, Nakanishi M, Harada M, Fujiwara M, Murakami M, Ueshima K, Nakao K. Kinoshita H, et al. Circulation. 2009 Sep 1;120(9):743-52. doi: 10.1161/CIRCULATIONAHA.109.857011. Epub 2009 Aug 17. Circulation. 2009. PMID: 19687356
Nocturnal hypercapnia with daytime normocapnia in patients with advanced pulmonary arterial hypertension awaiting lung transplantation.
Nakatsuka Y, Chen-Yoshikawa T, Kinoshita H, Aoyama A, Kubo H, Murase K, Hamada S, Takeyama H, Minami T, Takahashi N, Tanizawa K, Handa T, Hirai T, Date H, Chin K. Nakatsuka Y, et al. Among authors: kinoshita h. PLoS One. 2020 Apr 15;15(4):e0227775. doi: 10.1371/journal.pone.0227775. eCollection 2020. PLoS One. 2020. PMID: 32294102 Free PMC article.
Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart.
Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K. Kinoshita H, et al. Circ Res. 2010 Jun 25;106(12):1849-60. doi: 10.1161/CIRCRESAHA.109.208314. Epub 2010 May 6. Circ Res. 2010. PMID: 20448219
2,330 results