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TGFβ carrying exosomes in plasma: potential biomarkers of cancer progression in patients with head and neck squamous cell carcinoma.
Ludwig N, Yerneni SS, Harasymczuk M, Szczepański MJ, Głuszko A, Kukwa W, Jordan T, Spanier G, Taxis J, Spoerl S, Meier JK, Hinck CS, Campbell PG, Reichert TE, Hinck AP, Whiteside TL. Ludwig N, et al. Among authors: hinck cs, hinck ap. Br J Cancer. 2023 May;128(9):1733-1741. doi: 10.1038/s41416-023-02184-3. Epub 2023 Feb 21. Br J Cancer. 2023. PMID: 36810911 Free PMC article.
TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro-angiogenic phenotype.
Ludwig N, Yerneni SS, Azambuja JH, Pietrowska M, Widłak P, Hinck CS, Głuszko A, Szczepański MJ, Kärmer T, Kallinger I, Schulz D, Bauer RJ, Spanier G, Spoerl S, Meier JK, Ettl T, Razzo BM, Reichert TE, Hinck AP, Whiteside TL. Ludwig N, et al. Among authors: hinck cs, hinck ap. J Extracell Vesicles. 2022 Dec;11(12):e12294. doi: 10.1002/jev2.12294. J Extracell Vesicles. 2022. PMID: 36537293 Free PMC article.
The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cells.
Singh SP, Smyth DJ, Cunningham K, Mukundan A, Byeon CH, Hinck CS, White MPJ, Ciancia C, Wosowska N, Sanders A, Jin R, Lilla S, Zanivan S, Schoenherr C, Inman G, van Dinther M, Ten Dijke P, Hinck AP, Maizels RM. Singh SP, et al. Among authors: hinck ap. bioRxiv [Preprint]. 2023 Nov 15:2023.11.13.566701. doi: 10.1101/2023.11.13.566701. bioRxiv. 2023. PMID: 38014296 Free PMC article. Preprint.
Design of High Affinity Binders to Convex Protein Target Sites.
Yang W, Hicks DR, Ghosh A, Schwartze TA, Conventry B, Goreshnik I, Allen A, Halabiya SF, Kim CJ, Hinck CS, Lee DS, Bera AK, Li Z, Wang Y, Schlichthaerle T, Cao L, Huang B, Garrett S, Gerben SR, Rettie S, Heine P, Murray A, Edman N, Carter L, Stewart L, Almo S, Hinck AP, Baker D. Yang W, et al. Among authors: hinck ap. bioRxiv [Preprint]. 2024 May 2:2024.05.01.592114. doi: 10.1101/2024.05.01.592114. bioRxiv. 2024. PMID: 38746206 Free PMC article. Preprint.
Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation.
Daley JD, Mukherjee E, Tufino AC, Bailey N, Bhaskar S, Periyapatna N, MacFawn I, Kunning S, Hinck C, Bruno T, Olson AC, McAllister-Lucas LM, Hinck AP, Cooper K, Bao R, Cillo AR, Bailey KM. Daley JD, et al. Among authors: hinck ap. bioRxiv [Preprint]. 2024 May 10:2024.05.07.592974. doi: 10.1101/2024.05.07.592974. bioRxiv. 2024. PMID: 38766091 Free PMC article. Preprint.
TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts.
White SE, Schwartze TA, Mukundan A, Schoenherr C, Singh SP, van Dinther M, Cunningham KT, White MPJ, Campion T, Pritchard J, Hinck CS, Ten Dijke P, Inman G, Maizels RM, Hinck AP. White SE, et al. Among authors: hinck ap. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573140. doi: 10.1101/2023.12.22.573140. bioRxiv. 2023. PMID: 38187573 Free PMC article. Preprint.
101 results