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Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
Harris PA, Faucher N, George N, Eidam PM, King BW, White GV, Anderson NA, Bandyopadhyay D, Beal AM, Beneton V, Berger SB, Campobasso N, Campos S, Capriotti CA, Cox JA, Daugan A, Donche F, Fouchet MH, Finger JN, Geddes B, Gough PJ, Grondin P, Hoffman BL, Hoffman SJ, Hutchinson SE, Jeong JU, Jigorel E, Lamoureux P, Leister LK, Lich JD, Mahajan MK, Meslamani J, Mosley JE, Nagilla R, Nassau PM, Ng SL, Ouellette MT, Pasikanti KK, Potvain F, Reilly MA, Rivera EJ, Sautet S, Schaeffer MC, Sehon CA, Sun H, Thorpe JH, Totoritis RD, Ward P, Wellaway N, Wisnoski DD, Woolven JM, Bertin J, Marquis RW. Harris PA, et al. Among authors: george n. J Med Chem. 2019 May 23;62(10):5096-5110. doi: 10.1021/acs.jmedchem.9b00318. Epub 2019 May 2. J Med Chem. 2019. PMID: 31013427
Tissue-free liquid biopsies combining genomic and methylation signals for minimal residual disease detection in patients with early colorectal cancer from the UK TRACC Part B study.
Slater S, Bryant A, Aresu M, Begum R, Chen HC, Peckitt C, Lazaro-Alcausi R, Carter P, Anandappa G, Khakoo S, Melcher L, Potter V, Marti Marti F, Huang J, Branagan G, George N, Abulafi M, Duff S, Raja A, Gupta A, West N, Bucheit L, Rich T, Chau I, Cunningham D, Starling N. Slater S, et al. Among authors: george n. Clin Cancer Res. 2024 Jun 12. doi: 10.1158/1078-0432.CCR-24-0226. Online ahead of print. Clin Cancer Res. 2024. PMID: 38864835
Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN): a multicentre, open-label, randomised controlled phase 4 trial.
Wainwright CE, Vidmar S, Anderson V, Bourgeat P, Byrnes C, Carlin JB, Cheney J, Cooper P, Davidson A, Gailer N, Grayson-Collins J, Quittner A, Robertson C, Salvado O, Zannino D, Armstrong FD; ACFBAL; CF-GAIN Study Groups. Wainwright CE, et al. Lancet Respir Med. 2024 Jun 5:S2213-2600(24)00170-X. doi: 10.1016/S2213-2600(24)00170-X. Online ahead of print. Lancet Respir Med. 2024. PMID: 38851197
Is simultaneous diaphragmatic plication at Fontan completion beneficial?
Satsangi A, George N, Talwar S. Satsangi A, et al. Among authors: george n. Ann Pediatr Cardiol. 2023 Sep-Oct;16(5):387-388. doi: 10.4103/apc.apc_147_23. Epub 2024 Apr 1. Ann Pediatr Cardiol. 2023. PMID: 38766447 Free PMC article. No abstract available.
1,042 results