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Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma.
Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, Karasic TB, Abrams TA, Furuse J, Kelley RK, Cassier PA, Klümpen HJ, Chang HM, Chen LT, Tabernero J, Oh DY, Mahipal A, Moehler M, Mitchell EP, Komatsu Y, Masuda K, Ahn D, Epstein RS, Halim AB, Fu Y, Salimi T, Wacheck V, He Y, Liu M, Benhadji KA, Bridgewater JA; FOENIX-CCA2 Study Investigators. Goyal L, et al. Among authors: klumpen hj. N Engl J Med. 2023 Jan 19;388(3):228-239. doi: 10.1056/NEJMoa2206834. N Engl J Med. 2023. PMID: 36652354 Clinical Trial.
Short-term fasting alters cytochrome P450-mediated drug metabolism in humans.
Lammers LA, Achterbergh R, de Vries EM, van Nierop FS, Klümpen HJ, Soeters MR, Boelen A, Romijn JA, Mathôt RA. Lammers LA, et al. Among authors: klumpen hj. Drug Metab Dispos. 2015 Jun;43(6):819-28. doi: 10.1124/dmd.114.062299. Epub 2015 Mar 20. Drug Metab Dispos. 2015. PMID: 25795462 Clinical Trial.
Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity.
van Kuilenburg AB, Meijer J, Mul AN, Meinsma R, Schmid V, Dobritzsch D, Hennekam RC, Mannens MM, Kiechle M, Etienne-Grimaldi MC, Klümpen HJ, Maring JG, Derleyn VA, Maartense E, Milano G, Vijzelaar R, Gross E. van Kuilenburg AB, et al. Among authors: klumpen hj. Hum Genet. 2010 Nov;128(5):529-38. doi: 10.1007/s00439-010-0879-3. Epub 2010 Aug 29. Hum Genet. 2010. PMID: 20803296 Free PMC article.
Inhibitors of mTOR.
Klümpen HJ, Beijnen JH, Gurney H, Schellens JH. Klümpen HJ, et al. Oncologist. 2010;15(12):1262-9. doi: 10.1634/theoncologist.2010-0196. Epub 2010 Dec 8. Oncologist. 2010. PMID: 21147869 Free PMC article. Review.
An assisted structured reflection on life events and life goals in advanced cancer patients: Outcomes of a randomized controlled trial (Life InSight Application (LISA) study).
Kruizinga R, Scherer-Rath M, Schilderman JB, Hartog ID, Van Der Loos JP, Kotzé HP, Westermann AM, Klümpen HJ, Kortekaas F, Grootscholten C, Bossink F, Schrama J, Van De Vrande W, Schrama NA, Blokland W, De Vos FY, Kuin A, Meijer WG, Van Oijen MG, Sprangers MA, Van Laarhoven HW. Kruizinga R, et al. Among authors: klumpen hj. Palliat Med. 2019 Feb;33(2):221-231. doi: 10.1177/0269216318816005. Epub 2018 Dec 5. Palliat Med. 2019. PMID: 30516096 Free PMC article.
mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome.
Klümpen HJ, Queiroz KC, Spek CA, van Noesel CJ, Brink HC, de Leng WW, de Wilde RF, Mathus-Vliegen EM, Offerhaus GJ, Alleman MA, Westermann AM, Richel DJ. Klümpen HJ, et al. J Clin Oncol. 2011 Feb 20;29(6):e150-3. doi: 10.1200/JCO.2010.32.7825. Epub 2010 Dec 28. J Clin Oncol. 2011. PMID: 21189378 Free PMC article. No abstract available.
148 results