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LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells.
Hirabayashi D, Yamamoto KI, Maruyama A, Tomonobu N, Kinoshita R, Chen Y, Komalasari NLGY, Murata H, Gohara Y, Jiang F, Zhou J, Ruma IMW, Sumardika IW, Yamauchi A, Kuribayashi F, Toyooka S, Inoue Y, Sakaguchi M. Hirabayashi D, et al. Among authors: zhou j. Front Oncol. 2023 Feb 23;13:1142886. doi: 10.3389/fonc.2023.1142886. eCollection 2023. Front Oncol. 2023. PMID: 36910659 Free PMC article.
Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2.
Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M. Komalasari NLGY, et al. Among authors: zhou j. Front Oncol. 2023 Apr 4;13:1142907. doi: 10.3389/fonc.2023.1142907. eCollection 2023. Front Oncol. 2023. PMID: 37091157 Free PMC article.
Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface.
Takahashi T, Tomonobu N, Kinoshita R, Yamamoto KI, Murata H, Komalasari NLGY, Chen Y, Jiang F, Gohara Y, Ochi T, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Sakaguchi Y, Yamauchi A, Kuribayashi F, Kondo E, Inoue Y, Futami J, Toyooka S, Zamami Y, Sakaguchi M. Takahashi T, et al. Among authors: zhou j. Front Oncol. 2024 Mar 26;14:1371342. doi: 10.3389/fonc.2024.1371342. eCollection 2024. Front Oncol. 2024. PMID: 38595825 Free PMC article.
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