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Characteristics and outcomes for participants with congenital ichthyosis who responded to treatment with the topical isotretinoin formulation TMB-001: results from the Phase IIb CONTROL study.
Bunick CG, Teng JMC, Guenthner S, Marathe K, Kempers S, Eads K, Castelo-Soccio L, Mendelsohn AM, Raiz J, Murrell DF. Bunick CG, et al. Among authors: marathe k. Clin Exp Dermatol. 2023 Jul 7;48(7):765-769. doi: 10.1093/ced/llad105. Clin Exp Dermatol. 2023. PMID: 36928932 Clinical Trial.
The CONTROL study: A randomized, double-blind vehicle-controlled phase 2b study of novel topical isotretinoin formulation demonstrates improvement in recessive X-linked and autosomal recessive lamellar congenital ichthyosis.
Teng JMC, Bunick CG, Guenthner S, Murrell DF, Marathe K, Kempers S, Eads K, Mendelsohn AM, Raiz J, Tavakkol A, Castelo-Soccio L. Teng JMC, et al. Among authors: marathe k. J Am Acad Dermatol. 2022 Dec;87(6):1455-1458. doi: 10.1016/j.jaad.2022.07.028. Epub 2022 Jul 21. J Am Acad Dermatol. 2022. PMID: 35872261 Free article. Clinical Trial. No abstract available.
Phase IIb randomized CONTROL study demonstrates a novel topical isotretinoin formulation, TMB-001, is safe and effective in participants with either recessive X-linked or autosomal recessive lamellar congenital ichthyosis.
Murrell DF, Teng JMC, Guenthner S, Marathe K, Kempers S, Eads K, Castelo-Soccio L, Mendelsohn AM, Raiz J, Bunick CG. Murrell DF, et al. Among authors: marathe k. Clin Exp Dermatol. 2023 Jun 5;48(6):623-630. doi: 10.1093/ced/llad033. Clin Exp Dermatol. 2023. PMID: 36794376 Clinical Trial.
Topical Isotretinoin (TMB-001) Treatment for 12 Weeks Did Not Result in Clinically Relevant Laboratory Abnormalities in Participants with Congenital Ichthyosis in the Phase 2b CONTROL Study.
Marathe K, Teng JMC, Guenthner S, Bunick CG, Kempers S, Eads K, Castelo-Soccio L, Mendelsohn AM, Raiz J, Murrell DF. Marathe K, et al. Dermatol Ther (Heidelb). 2023 Jun;13(6):1255-1264. doi: 10.1007/s13555-023-00923-1. Epub 2023 May 11. Dermatol Ther (Heidelb). 2023. PMID: 37170057 Free PMC article.
Hypopigmented lesions on the neck of a 9-year-old girl.
Hancock J, Shaughnessy C, Marathe K. Hancock J, et al. Among authors: marathe k. Pediatr Dermatol. 2021 Jul;38(4):935-936. doi: 10.1111/pde.14577. Pediatr Dermatol. 2021. PMID: 34448227 No abstract available.
Eruptive milia during isotretinoin therapy.
Farmer W, Cheng K, Marathe K. Farmer W, et al. Among authors: marathe k. Pediatr Dermatol. 2017 Nov;34(6):728-729. doi: 10.1111/pde.13270. Epub 2017 Sep 21. Pediatr Dermatol. 2017. PMID: 28940619
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