Stephan C - Search Results

1

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo.

Fan F, Ghosh S, Powell R, Roszik J, Park Y, Sobieski M, Sorokin A, Stephan C, Kopetz S, Ellis LM, Bhattacharya R. Fan F, et al. Among authors: stephan c. PLoS One. 2023 Mar 23;18(3):e0281063. doi: 10.1371/journal.pone.0281063. eCollection 2023. PLoS One. 2023. PMID: 36952536 Free PMC article.

2

Agents that stabilize mutated von Hippel-Lindau (VHL) protein: results of a high-throughput screen to identify compounds that modulate VHL proteostasis.

Ding Z, German P, Bai S, Feng Z, Gao M, Si W, Sobieski MM, Stephan CC, Mills GB, Jonasch E. Ding Z, et al. Among authors: stephan cc. J Biomol Screen. 2012 Jun;17(5):572-80. doi: 10.1177/1087057112436557. Epub 2012 Feb 21. J Biomol Screen. 2012. PMID: 22357874 Free PMC article.

3

A high content clonogenic survival drug screen identifies mek inhibitors as potent radiation sensitizers for KRAS mutant non-small-cell lung cancer.

Lin SH, Zhang J, Giri U, Stephan C, Sobieski M, Zhong L, Mason KA, Molkentine J, Thames HD, Yoo SS, Heymach JV. Lin SH, et al. Among authors: stephan c. J Thorac Oncol. 2014 Jul;9(7):965-973. doi: 10.1097/JTO.0000000000000199. J Thorac Oncol. 2014. PMID: 24922006 Free PMC article.

4

Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy.

Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Guan F, et al. Among authors: stephan c. Sci Rep. 2015 May 18;5:9850. doi: 10.1038/srep09850. Sci Rep. 2015. PMID: 25984967 Free PMC article.

5

Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.

Kogiso M, Qi L, Lindsay H, Huang Y, Zhao X, Liu Z, Braun FK, Du Y, Zhang H, Bae G, Zhao S, Injac SG, Sobieski M, Brunell D, Mehta V, Tran D, Murray J, Baxter PA, Yuan XJ, Su JM, Adesina A, Perlaky L, Chintagumpala M, Parsons DW, Lau CC, Stephan CC, Lu X, Li XN. Kogiso M, et al. Among authors: stephan cc. Oncotarget. 2017 Sep 8;8(50):87455-87471. doi: 10.18632/oncotarget.20713. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152094 Free PMC article.

6

Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells.

Chowdhury P, Powell RT, Stephan C, Uray IP, Talley T, Karki M, Tripathi DN, Park YS, Mancini MA, Davies P, Dere R. Chowdhury P, et al. Among authors: stephan c. J Cell Sci. 2018 Dec 14;131(24):jcs219923. doi: 10.1242/jcs.219923. J Cell Sci. 2018. PMID: 30518623 Free PMC article.

7

GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer.

Vijay GV, Zhao N, Den Hollander P, Toneff MJ, Joseph R, Pietila M, Taube JH, Sarkar TR, Ramirez-Pena E, Werden SJ, Shariati M, Gao R, Sobieski M, Stephan CC, Sphyris N, Miura N, Davies P, Chang JT, Soundararajan R, Rosen JM, Mani SA. Vijay GV, et al. Among authors: stephan cc. Breast Cancer Res. 2019 Mar 7;21(1):37. doi: 10.1186/s13058-019-1125-0. Breast Cancer Res. 2019. PMID: 30845991 Free PMC article.

8

High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na⁺ channel complex.

Wadsworth PA, Folorunso O, Nguyen N, Singh AK, D'Amico D, Powell RT, Brunell D, Allen J, Stephan C, Laezza F. Wadsworth PA, et al. Among authors: stephan c. Sci Rep. 2019 Nov 15;9(1):16890. doi: 10.1038/s41598-019-53110-8. Sci Rep. 2019. PMID: 31729429 Free PMC article.

9

Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns.

Ma D, Bronk L, Kerr M, Sobieski M, Chen M, Geng C, Yiu J, Wang X, Sahoo N, Cao W, Zhang X, Stephan C, Mohan R, Grosshans DR, Guan F. Ma D, et al. Among authors: stephan c. Sci Rep. 2020 Feb 21;10(1):3199. doi: 10.1038/s41598-020-60246-5. Sci Rep. 2020. PMID: 32081928 Free PMC article.

10

Pharmacologic profiling of patient-derived xenograft models of primary treatment-naïve triple-negative breast cancer.

Powell RT, Redwood A, Liu X, Guo L, Cai S, Zhou X, Tu Y, Zhang X, Qi Y, Jiang Y, Echeverria G, Feng N, Ma X, Giuliani V, Marszalek JR, Heffernan TP, Vellano CP, White JB, Stephan C, Davies PJ, Moulder S, Symmans WF, Chang JT, Piwnica-Worms H. Powell RT, et al. Among authors: stephan c. Sci Rep. 2020 Oct 21;10(1):17899. doi: 10.1038/s41598-020-74882-4. Sci Rep. 2020. PMID: 33087803 Free PMC article.

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