Denu RA - Search Results

1

Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer.

Tucker JB, Bonema SC, García-Varela R, Denu RA, Hu Y, McGregor SM, Burkard ME, Weaver BA. Tucker JB, et al. Among authors: denu ra. Cancer Res Commun. 2023 Jan 12;3(1):54-65. doi: 10.1158/2767-9764.CRC-22-0302. eCollection 2023 Jan. Cancer Res Commun. 2023. PMID: 36968230 Free PMC article.

2

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer.

Choudhary A, Zachek B, Lera RF, Zasadil LM, Lasek A, Denu RA, Kim H, Kanugh C, Laffin JJ, Harter JM, Wisinski KB, Saha S, Weaver BA, Burkard ME. Choudhary A, et al. Among authors: denu ra. Mol Cancer Ther. 2016 Jan;15(1):48-59. doi: 10.1158/1535-7163.MCT-15-0527. Epub 2015 Nov 19. Mol Cancer Ther. 2016. PMID: 26586723 Free PMC article.

3

Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer.

Denu RA, Zasadil LM, Kanugh C, Laffin J, Weaver BA, Burkard ME. Denu RA, et al. BMC Cancer. 2016 Jan 29;16:47. doi: 10.1186/s12885-016-2083-x. BMC Cancer. 2016. PMID: 26832928 Free PMC article.

4

Synchronous Bilateral Breast Cancer in a Patient With Nager Syndrome.

Denu RA, Burkard ME. Denu RA, et al. Clin Breast Cancer. 2017 Jun;17(3):e151-e153. doi: 10.1016/j.clbc.2016.12.009. Epub 2017 Jan 5. Clin Breast Cancer. 2017. PMID: 28139434 Free PMC article.

5

Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma.

Denu RA, Shabbir M, Nihal M, Singh CK, Longley BJ, Burkard ME, Ahmad N. Denu RA, et al. Mol Cancer Res. 2018 Mar;16(3):517-527. doi: 10.1158/1541-7786.MCR-17-0197. Epub 2018 Jan 12. Mol Cancer Res. 2018. PMID: 29330283 Free PMC article.

6

Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131).

Denu RA, Sass MM, Johnson JM, Potts GK, Choudhary A, Coon JJ, Burkard ME. Denu RA, et al. J Biol Chem. 2019 Apr 19;294(16):6531-6549. doi: 10.1074/jbc.RA118.004867. Epub 2019 Feb 25. J Biol Chem. 2019. PMID: 30804208 Free PMC article.

7

Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.

Denu RA, Kaur G, Sass MM, Lakkaraju A, Burkard ME. Denu RA, et al. Mol Cancer Res. 2020 Jan;18(1):33-45. doi: 10.1158/1541-7786.MCR-19-0509. Epub 2019 Oct 11. Mol Cancer Res. 2020. PMID: 31604847 Free PMC article.

8

Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer.

Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Singh A, et al. Among authors: denu ra. Mol Oncol. 2020 Aug;14(8):1898-1909. doi: 10.1002/1878-0261.12687. Epub 2020 May 19. Mol Oncol. 2020. PMID: 32255253 Free PMC article.

9

Analysis of the "centrosome-ome" identifies MCPH1 deletion as a cause of centrosome amplification in human cancer.

Denu RA, Burkard ME. Denu RA, et al. Sci Rep. 2020 Jul 17;10(1):11921. doi: 10.1038/s41598-020-68629-4. Sci Rep. 2020. PMID: 32681070 Free PMC article.

10

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability.

Matson DR, Denu RA, Zasadil LM, Burkard ME, Weaver BA, Flynn C, Stukenberg PT. Matson DR, et al. Among authors: denu ra. BMC Cancer. 2021 Feb 23;21(1):186. doi: 10.1186/s12885-021-07893-7. BMC Cancer. 2021. PMID: 33622270 Free PMC article.

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