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CRISPR screens identify gene targets at breast cancer risk loci.
Tuano NK, Beesley J, Manning M, Shi W, Perlaza-Jimenez L, Malaver-Ortega LF, Paynter JM, Black D, Civitarese A, McCue K, Hatzipantelis A, Hillman K, Kaufmann S, Sivakumaran H, Polo JM, Reddel RR, Band V, French JD, Edwards SL, Powell DR, Chenevix-Trench G, Rosenbluh J. Tuano NK, et al. Among authors: powell dr. Genome Biol. 2023 Mar 29;24(1):59. doi: 10.1186/s13059-023-02898-w. Genome Biol. 2023. PMID: 36991492 Free PMC article.
Cell Type of Origin Dictates the Route to Pluripotency.
Nefzger CM, Rossello FJ, Chen J, Liu X, Knaupp AS, Firas J, Paynter JM, Pflueger J, Buckberry S, Lim SM, Williams B, Alaei S, Faye-Chauhan K, Petretto E, Nilsson SK, Lister R, Ramialison M, Powell DR, Rackham OJL, Polo JM. Nefzger CM, et al. Among authors: powell dr. Cell Rep. 2017 Dec 5;21(10):2649-2660. doi: 10.1016/j.celrep.2017.11.029. Cell Rep. 2017. PMID: 29212013 Free article.
Transcriptome analysis of the zebrafish atoh7-/- Mutant, lakritz, highlights Atoh7-dependent genetic networks with potential implications for human eye diseases.
Covello G, Rossello FJ, Filosi M, Gajardo F, Duchemin AL, Tremonti BF, Eichenlaub M, Polo JM, Powell D, Ngai J, Allende ML, Domenici E, Ramialison M, Poggi L. Covello G, et al. FASEB Bioadv. 2020 Jun 27;2(7):434-448. doi: 10.1096/fba.2020-00030. eCollection 2020 Jul. FASEB Bioadv. 2020. PMID: 32676583 Free PMC article.
Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium.
Jardé T, Chan WH, Rossello FJ, Kaur Kahlon T, Theocharous M, Kurian Arackal T, Flores T, Giraud M, Richards E, Chan E, Kerr G, Engel RM, Prasko M, Donoghue JF, Abe SI, Phesse TJ, Nefzger CM, McMurrick PJ, Powell DR, Daly RJ, Polo JM, Abud HE. Jardé T, et al. Among authors: powell dr. Cell Stem Cell. 2020 Oct 1;27(4):646-662.e7. doi: 10.1016/j.stem.2020.06.021. Epub 2020 Jul 20. Cell Stem Cell. 2020. PMID: 32693086 Free article.
Reprogramming roadmap reveals route to human induced trophoblast stem cells.
Liu X, Ouyang JF, Rossello FJ, Tan JP, Davidson KC, Valdes DS, Schröder J, Sun YBY, Chen J, Knaupp AS, Sun G, Chy HS, Huang Z, Pflueger J, Firas J, Tano V, Buckberry S, Paynter JM, Larcombe MR, Poppe D, Choo XY, O'Brien CM, Pastor WA, Chen D, Leichter AL, Naeem H, Tripathi P, Das PP, Grubman A, Powell DR, Laslett AL, David L, Nilsson SK, Clark AT, Lister R, Nefzger CM, Martelotto LG, Rackham OJL, Polo JM. Liu X, et al. Among authors: powell dr. Nature. 2020 Oct;586(7827):101-107. doi: 10.1038/s41586-020-2734-6. Epub 2020 Sep 16. Nature. 2020. PMID: 32939092
3D-cardiomics: A spatial transcriptional atlas of the mammalian heart.
Mohenska M, Tan NM, Tokolyi A, Furtado MB, Costa MW, Perry AJ, Hatwell-Humble J, van Duijvenboden K, Nim HT, Ji YMM, Charitakis N, Bienroth D, Bolk F, Vivien C, Knaupp AS, Powell DR, Elliott DA, Porrello ER, Nilsson SK, Del Monte-Nieto G, Rosenthal NA, Rossello FJ, Polo JM, Ramialison M. Mohenska M, et al. Among authors: powell dr. J Mol Cell Cardiol. 2022 Feb;163:20-32. doi: 10.1016/j.yjmcc.2021.09.011. Epub 2021 Oct 5. J Mol Cell Cardiol. 2022. PMID: 34624332
425 results