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A framework for setting enrollment goals to ensure participant diversity in sponsored clinical trials in the United States.
Cullen MR, Lemeshow AR, Amaro S, Bandera EV, Cooper LA, Kawachi I, Lunyera J, McKinley L, Poss CS, Rottas MM, Schachterle SE, Thadeio PF, Russo LJ. Cullen MR, et al. Among authors: poss cs. Contemp Clin Trials. 2023 Jun;129:107184. doi: 10.1016/j.cct.2023.107184. Epub 2023 Apr 11. Contemp Clin Trials. 2023. PMID: 37054773 Free article.
Piperazinyl CCR1 antagonists--optimization of human liver microsome stability.
Brown MF, Bahnck KB, Blumberg LC, Brissette WH, Burrell SA, Driscoll JP, Fedeles F, Fisher MB, Foti RS, Gladue RP, Guzman-Martinez A, Hayward MM, Lira PD, Lillie BM, Lu Y, Lundquist GD, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Roache JH, Shavnya A, Shepard RM, Trevena KA, Tylaska LA. Brown MF, et al. Among authors: poss cs. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3109-12. doi: 10.1016/j.bmcl.2007.03.037. Epub 2007 Mar 15. Bioorg Med Chem Lett. 2007. PMID: 17383873
Novel CCR1 antagonists with improved metabolic stability.
Brown MF, Avery M, Brissette WH, Chang JH, Colizza K, Conklyn M, DiRico AP, Gladue RP, Kath JC, Krueger SS, Lira PD, Lillie BM, Lundquist GD, Mairs EN, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Rossulek MI, Shepard RM, Sims J, Strelevitz TJ, Truesdell S, Tylaska LA, Yoon K, Zheng D. Brown MF, et al. Among authors: poss cs. Bioorg Med Chem Lett. 2004 May 3;14(9):2175-9. doi: 10.1016/j.bmcl.2004.02.022. Bioorg Med Chem Lett. 2004. PMID: 15081003
Potent small molecule CCR1 antagonists.
Kath JC, Brissette WH, Brown MF, Conklyn M, DiRico AP, Dorff P, Gladue RP, Lillie BM, Lira PD, Mairs EN, Martin WH, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Stock IA, Tylaska LA, Zheng D. Kath JC, et al. Among authors: poss cs. Bioorg Med Chem Lett. 2004 May 3;14(9):2169-73. doi: 10.1016/j.bmcl.2004.02.021. Bioorg Med Chem Lett. 2004. PMID: 15081002
CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.
Gladue RP, Tylaska LA, Brissette WH, Lira PD, Kath JC, Poss CS, Brown MF, Paradis TJ, Conklyn MJ, Ogborne KT, McGlynn MA, Lillie BM, DiRico AP, Mairs EN, McElroy EB, Martin WH, Stock IA, Shepard RM, Showell HJ, Neote K. Gladue RP, et al. Among authors: poss cs. J Biol Chem. 2003 Oct 17;278(42):40473-80. doi: 10.1074/jbc.M306875200. Epub 2003 Aug 7. J Biol Chem. 2003. PMID: 12909630 Free article.