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The ubiquitin ligase Siah2 and the hypoxia response.
Nakayama K, Qi J, Ronai Z. Nakayama K, et al. Mol Cancer Res. 2009 Apr;7(4):443-51. doi: 10.1158/1541-7786.MCR-08-0458. Mol Cancer Res. 2009. PMID: 19372575 Free PMC article. Review.
Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice.
Li S, Ezhevsky S, Dewing A, Cato MH, Scortegagna M, Bhoumik A, Breitwieser W, Braddock D, Eroshkin A, Qi J, Chen M, Kim JY, Jones S, Jones N, Rickert R, Ronai ZA. Li S, et al. Among authors: ronai za. Genes Cancer. 2010 Apr 1;1(4):316-330. doi: 10.1177/1947601910370700. Genes Cancer. 2010. PMID: 20740050 Free PMC article.
Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.
Feng Y, Lau E, Scortegagna M, Ruller C, De SK, Barile E, Krajewski S, Aza-Blanc P, Williams R, Pinkerton AB, Jackson M, Chin L, Pellecchia M, Bosenberg M, Ronai ZA. Feng Y, et al. Among authors: ronai za. Pigment Cell Melanoma Res. 2013 Jan;26(1):136-42. doi: 10.1111/pcmr.12033. Epub 2012 Nov 2. Pigment Cell Melanoma Res. 2013. PMID: 23035722 Free PMC article.
Regulators and effectors of Siah ubiquitin ligases.
Qi J, Kim H, Scortegagna M, Ronai ZA. Qi J, et al. Among authors: ronai za. Cell Biochem Biophys. 2013 Sep;67(1):15-24. doi: 10.1007/s12013-013-9636-2. Cell Biochem Biophys. 2013. PMID: 23700162 Free PMC article. Review.
Fine tuning of the UPR by the ubiquitin ligases Siah1/2.
Scortegagna M, Kim H, Li JL, Yao H, Brill LM, Han J, Lau E, Bowtell D, Haddad G, Kaufman RJ, Ronai ZA. Scortegagna M, et al. Among authors: ronai za. PLoS Genet. 2014 May 8;10(5):e1004348. doi: 10.1371/journal.pgen.1004348. eCollection 2014 May. PLoS Genet. 2014. PMID: 24809345 Free PMC article.
PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets.
Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, Bosenberg M, Ronai ZA. Scortegagna M, et al. Among authors: ronai za. Cancer Res. 2015 Apr 1;75(7):1399-412. doi: 10.1158/0008-5472.CAN-14-2785. Epub 2015 Feb 24. Cancer Res. 2015. PMID: 25712345 Free PMC article.
171 results