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Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice.
Krishnarajah S, Ingelfinger F, Friebel E, Cansever D, Amorim A, Andreadou M, Bamert D, Litscher G, Lutz M, Mayoux M, Mundt S, Ridder F, Sparano C, Stifter SA, Ulutekin C, Unger S, Vermeer M, Zwicky P, Greter M, Tugues S, De Feo D, Becher B. Krishnarajah S, et al. Among authors: amorim a. Nat Aging. 2022 Jan;2(1):74-89. doi: 10.1038/s43587-021-00148-x. Epub 2021 Dec 16. Nat Aging. 2022. PMID: 37118354
Skipping adolescence to become super-inflammatory monocytes.
Becher B, De Feo D, Amorim A, Greter M. Becher B, et al. Among authors: amorim a. Nat Immunol. 2020 May;21(5):491-492. doi: 10.1038/s41590-020-0652-2. Nat Immunol. 2020. PMID: 32313243 No abstract available.
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.
Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B. Tugues S, et al. Among authors: amorim a. Sci Transl Med. 2018 Nov 28;10(469):eaat8410. doi: 10.1126/scitranslmed.aat8410. Sci Transl Med. 2018. PMID: 30487251
Pericytes regulate vascular immune homeostasis in the CNS.
Török O, Schreiner B, Schaffenrath J, Tsai HC, Maheshwari U, Stifter SA, Welsh C, Amorim A, Sridhar S, Utz SG, Mildenberger W, Nassiri S, Delorenzi M, Aguzzi A, Han MH, Greter M, Becher B, Keller A. Török O, et al. Among authors: amorim a. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2016587118. doi: 10.1073/pnas.2016587118. Proc Natl Acad Sci U S A. 2021. PMID: 33653955 Free PMC article.
Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg development.
Haftmann C, Zwicky P, Ingelfinger F, Mair F, Floess S, Riedel R, Durek P, Spalinger MR, Friebel E, Leung BP, Lutz M, Puertas N, Amorim A, Schärli S, Becher B, Kisielow J, Waisman A, Mashreghi MF, Huehn J, Becher B. Haftmann C, et al. Among authors: amorim a. Sci Immunol. 2021 Nov 19;6(65):eabf3111. doi: 10.1126/sciimmunol.abf3111. Epub 2021 Nov 19. Sci Immunol. 2021. PMID: 34797691
IL-17 controls central nervous system autoimmunity through the intestinal microbiome.
Regen T, Isaac S, Amorim A, Núñez NG, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov IA, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez EJC, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A. Regen T, et al. Among authors: amorim a. Sci Immunol. 2021 Feb 5;6(56):eaaz6563. doi: 10.1126/sciimmunol.aaz6563. Sci Immunol. 2021. PMID: 33547052
MicroRNA-181a regulates IFN-γ expression in effector CD8+ T cell differentiation.
Amado T, Amorim A, Enguita FJ, Romero PV, Inácio D, de Miranda MP, Winter SJ, Simas JP, Krueger A, Schmolka N, Silva-Santos B, Gomes AQ. Amado T, et al. Among authors: amorim a. J Mol Med (Berl). 2020 Feb;98(2):309-320. doi: 10.1007/s00109-019-01865-y. Epub 2020 Jan 30. J Mol Med (Berl). 2020. PMID: 32002568 Free PMC article.
1,027 results