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Covalent Inhibition by a Natural Product-Inspired Latent Electrophile.
Byun DP, Ritchie J, Jung Y, Holewinski R, Kim HR, Tagirasa R, Ivanic J, Weekley CM, Parker MW, Andresson T, Yoo E. Byun DP, et al. Among authors: holewinski r. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15. J Am Chem Soc. 2023. PMID: 37183434 Free PMC article.
Investigating the NRAS 5' UTR as a target for small molecules.
Balaratnam S, Torrey ZR, Calabrese DR, Banco MT, Yazdani K, Liang X, Fullenkamp CR, Seshadri S, Holewinski RJ, Andresson T, Ferré-D'Amaré AR, Incarnato D, Schneekloth JS Jr. Balaratnam S, et al. Among authors: holewinski rj. Cell Chem Biol. 2023 Jun 15;30(6):643-657.e8. doi: 10.1016/j.chembiol.2023.05.004. Epub 2023 May 30. Cell Chem Biol. 2023. PMID: 37257453 Free article.
Chemical tools to define and manipulate interferon-inducible Ubl protease USP18.
Davis GJ, Omole AO, Jung Y, Rut W, Holewinski R, Suazo KF, Kim HR, Yang M, Andresson T, Drag M, Yoo E. Davis GJ, et al. Among authors: holewinski r. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588544. doi: 10.1101/2024.04.08.588544. bioRxiv. 2024. PMID: 38645224 Free PMC article. Preprint.
Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression.
Amin R, Ha NH, Qiu T, Holewinski R, Lam KC, Lopès A, Liu H, Tran AD, Lee MP, Gamage ST, Andresson T, Goldszmid RS, Meier JL, Hunter KW. Amin R, et al. Among authors: holewinski r. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577116. doi: 10.1101/2024.01.24.577116. bioRxiv. 2024. PMID: 38410432 Free PMC article. Preprint.
IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma.
Bolomsky A, Ceribelli M, Scheich S, Rinaldi K, Huang DW, Chakraborty P, Pham L, Wright GW, Hsiao T, Morris V, Choi J, Phelan JD, Holewinski RJ, Andresson T, Wisniewski J, Riley D, Pittaluga S, Hill E, Thomas CJ, Muppidi J, Young RM. Bolomsky A, et al. Among authors: holewinski rj. Cancer Cell. 2024 Jun 14:S1535-6108(24)00217-4. doi: 10.1016/j.ccell.2024.05.026. Online ahead of print. Cancer Cell. 2024. PMID: 38906156
Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly.
Buckenmeyer MJ, Brooks EA, Taylor MS, Yang L, Holewinski RJ, Meyer TJ, Galloux M, Garmendia-Cedillos M, Pohida TJ, Andresson T, St Croix B, Wolf MT. Buckenmeyer MJ, et al. Among authors: holewinski rj. bioRxiv [Preprint]. 2024 Mar 22:2024.03.19.585805. doi: 10.1101/2024.03.19.585805. bioRxiv. 2024. PMID: 38903106 Free PMC article. Preprint.
42 results