Vakulskas CA - Search Results

1

Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell Replacement.

Cooke JA, Voigt AP, Collingwood MA, Stone NE, Whitmore SS, DeLuca AP, Burnight ER, Anfinson KR, Vakulskas CA, Reutzel AJ, Daggett HT, Andorf JL, Stone EM, Mullins RF, Tucker BA. Cooke JA, et al. Among authors: vakulskas ca. Stem Cells Transl Med. 2023 Jun 15;12(6):365-378. doi: 10.1093/stcltm/szad028. Stem Cells Transl Med. 2023. PMID: 37221451 Free PMC article.

2

Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34⁺ hematopoietic stem and progenitor cells.

Cromer MK, Majeti KR, Rettig GR, Murugan K, Kurgan GL, Bode NM, Hampton JP, Vakulskas CA, Behlke MA, Porteus MH. Cromer MK, et al. Among authors: vakulskas ca. Mol Ther. 2023 Apr 5;31(4):1074-1087. doi: 10.1016/j.ymthe.2023.02.011. Epub 2023 Feb 15. Mol Ther. 2023. PMID: 36793210 Free PMC article.

3

Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants.

Zhang L, Li G, Zhang Y, Cheng Y, Roberts N, Glenn SE, DeZwaan-McCabe D, Rube HT, Manthey J, Coleman G, Vakulskas CA, Qi Y. Zhang L, et al. Among authors: vakulskas ca. Genome Biol. 2023 Apr 30;24(1):102. doi: 10.1186/s13059-023-02929-6. Genome Biol. 2023. PMID: 37122009 Free PMC article.

4

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells.

Baik R, Cromer MK, Glenn SE, Vakulskas CA, Chmielewski KO, Dudek AM, Feist WN, Klermund J, Shipp S, Cathomen T, Dever DP, Porteus MH. Baik R, et al. Among authors: vakulskas ca. Nat Commun. 2024 Jan 2;15(1):111. doi: 10.1038/s41467-023-43413-w. Nat Commun. 2024. PMID: 38169468 Free PMC article.

5

Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency.

Pavel-Dinu M, Gardner CL, Nakauchi Y, Kawai T, Delmonte OM, Palterer B, Bosticardo M, Pala F, Viel S, Malech HL, Ghanim HY, Bode NM, Kurgan GL, Detweiler AM, Vakulskas CA, Neff NF, Sheikali A, Menezes ST, Chrobok J, Hernández González EM, Majeti R, Notarangelo LD, Porteus MH. Pavel-Dinu M, et al. Among authors: vakulskas ca. Blood Adv. 2024 Apr 9;8(7):1820-1833. doi: 10.1182/bloodadvances.2023011766. Blood Adv. 2024. PMID: 38096800 Free PMC article.

6

Generation of the transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein in the T0 generation.

Su H, Wang Y, Xu J, Omar AA, Grosser JW, Calovic M, Zhang L, Feng Y, Vakulskas CA, Wang N. Su H, et al. Among authors: vakulskas ca. Nat Commun. 2023 Jul 5;14(1):3957. doi: 10.1038/s41467-023-39714-9. Nat Commun. 2023. PMID: 37402755 Free PMC article.

7

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.

Yarnall MTN, Ioannidi EI, Schmitt-Ulms C, Krajeski RN, Lim J, Villiger L, Zhou W, Jiang K, Garushyants SK, Roberts N, Zhang L, Vakulskas CA, Walker JA 2nd, Kadina AP, Zepeda AE, Holden K, Ma H, Xie J, Gao G, Foquet L, Bial G, Donnelly SK, Miyata Y, Radiloff DR, Henderson JM, Ujita A, Abudayyeh OO, Gootenberg JS. Yarnall MTN, et al. Among authors: vakulskas ca. Nat Biotechnol. 2023 Apr;41(4):500-512. doi: 10.1038/s41587-022-01527-4. Epub 2022 Nov 24. Nat Biotechnol. 2023. PMID: 36424489 Free PMC article.

8

Amount of Cas9 protein introduced into mouse embryos via electroporation affects the genome-editing rate.

Wake Y, Vakulskas CA, Glenn SE, Kaneko T. Wake Y, et al. Among authors: vakulskas ca. J Reprod Dev. 2022 Oct 6;68(5):307-311. doi: 10.1262/jrd.2022-067. Epub 2022 Jul 14. J Reprod Dev. 2022. PMID: 35831117 Free PMC article.

9

Highly Efficient Genome Editing in Plant Protoplasts by Ribonucleoprotein Delivery of CRISPR-Cas12a Nucleases.

Zhang Y, Cheng Y, Fang H, Roberts N, Zhang L, Vakulskas CA, Niedz RP, Culver JN, Qi Y. Zhang Y, et al. Among authors: vakulskas ca. Front Genome Ed. 2022 Jan 31;4:780238. doi: 10.3389/fgeed.2022.780238. eCollection 2022. Front Genome Ed. 2022. PMID: 35174354 Free PMC article. Review.

10

Efficiency, Specificity and Temperature Sensitivity of Cas9 and Cas12a RNPs for DNA-free Genome Editing in Plants.

Banakar R, Schubert M, Kurgan G, Rai KM, Beaudoin SF, Collingwood MA, Vakulskas CA, Wang K, Zhang F. Banakar R, et al. Among authors: vakulskas ca. Front Genome Ed. 2022 Jan 12;3:760820. doi: 10.3389/fgeed.2021.760820. eCollection 2021. Front Genome Ed. 2022. PMID: 35098208 Free PMC article.

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