Dwyer AR - Search Results

1

Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4.

Dwyer AR, Perez Kerkvliet C, Truong TH, Hagen KM, Krutilina RI, Parke DN, Oakley RH, Liddle C, Cidlowski JA, Seagroves TN, Lange CA. Dwyer AR, et al. Endocrinology. 2023 Jun 6;164(7):bqad083. doi: 10.1210/endocr/bqad083. Endocrinology. 2023. PMID: 37224504 Free PMC article.

2

Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates.

Truong TH, Dwyer AR, Diep CH, Hu H, Hagen KM, Lange CA. Truong TH, et al. Among authors: dwyer ar. Endocrinology. 2019 Feb 1;160(2):430-446. doi: 10.1210/en.2018-00990. Endocrinology. 2019. PMID: 30597041 Free PMC article.

3

90 YEARS OF PROGESTERONE: Steroid receptors as MAPK signaling sensors in breast cancer: let the fates decide.

Dwyer AR, Truong TH, Ostrander JH, Lange CA. Dwyer AR, et al. J Mol Endocrinol. 2020 Jul;65(1):T35-T48. doi: 10.1530/JME-19-0274. J Mol Endocrinol. 2020. PMID: 32209723 Free PMC article. Review.

4

Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer.

Perez Kerkvliet C, Dwyer AR, Diep CH, Oakley RH, Liddle C, Cidlowski JA, Lange CA. Perez Kerkvliet C, et al. Among authors: dwyer ar. Breast Cancer Res. 2020 May 1;22(1):39. doi: 10.1186/s13058-020-01277-8. Breast Cancer Res. 2020. PMID: 32357907 Free PMC article.

5

Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer.

Dwyer AR, Truong TH, Kerkvliet CP, Paul KV, Kabos P, Sartorius CA, Lange CA. Dwyer AR, et al. Br J Cancer. 2021 Jan;124(1):217-227. doi: 10.1038/s41416-020-01094-y. Epub 2020 Nov 4. Br J Cancer. 2021. PMID: 33144693 Free PMC article.

6

Breast Tumor Kinase (Brk/PTK6) Mediates Advanced Cancer Phenotypes via SH2-Domain Dependent Activation of RhoA and Aryl Hydrocarbon Receptor (AhR) Signaling.

Dwyer AR, Kerkvliet CP, Krutilina RI, Playa HC, Parke DN, Thomas WA, Smeester BA, Moriarity BS, Seagroves TN, Lange CA. Dwyer AR, et al. Mol Cancer Res. 2021 Feb;19(2):329-345. doi: 10.1158/1541-7786.MCR-20-0295. Epub 2020 Nov 10. Mol Cancer Res. 2021. PMID: 33172975 Free PMC article.

7

Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.

Prekovic S, Chalkiadakis T, Roest M, Roden D, Lutz C, Schuurman K, Opdam M, Hoekman L, Abbott N, Tesselaar T, Wajahat M, Dwyer AR, Mayayo-Peralta I, Gomez G, Altelaar M, Beijersbergen R, Győrffy B, Young L, Linn S, Jonkers J, Tilley W, Hickey T, Vareslija D, Swarbrick A, Zwart W. Prekovic S, et al. Among authors: dwyer ar. EMBO Mol Med. 2023 Dec 7;15(12):e17737. doi: 10.15252/emmm.202317737. Epub 2023 Oct 30. EMBO Mol Med. 2023. PMID: 37902007 Free PMC article.

8

Selective inhibition of CDK9 in triple negative breast cancer.

Mustafa EH, Laven-Law G, Kikhtyak Z, Nguyen V, Ali S, Pace AA, Iggo R, Kebede A, Noll B, Wang S, Winter JM, Dwyer AR, Tilley WD, Hickey TE. Mustafa EH, et al. Among authors: dwyer ar. Oncogene. 2024 Jan;43(3):202-215. doi: 10.1038/s41388-023-02892-3. Epub 2023 Nov 24. Oncogene. 2024. PMID: 38001268 Free PMC article.

9

The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.

Hosseinzadeh L, Kikhtyak Z, Laven-Law G, Pederson SM, Puiu CG, D'Santos CS, Lim E, Carroll JS, Tilley WD, Dwyer AR, Hickey TE. Hosseinzadeh L, et al. Among authors: dwyer ar. Genome Biol. 2024 Feb 5;25(1):44. doi: 10.1186/s13059-023-03161-y. Genome Biol. 2024. PMID: 38317241 Free PMC article.

10

Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer.

Hickey TE, Dwyer AR, Tilley WD. Hickey TE, et al. Among authors: dwyer ar. Br J Cancer. 2021 Dec;125(12):1599-1601. doi: 10.1038/s41416-021-01478-8. Epub 2021 Jul 22. Br J Cancer. 2021. PMID: 34294894 Free PMC article.

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