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Removal of AMR plasmids using a mobile, broad host-range CRISPR-Cas9 delivery tool.
Microbiology (Reading). 2023 May;169(5):001334. doi: 10.1099/mic.0.001334.
Microbiology (Reading). 2023.
PMID: 37226834
Free PMC article.
CRISPR-Cas antimicrobials: Challenges and future prospects.
Pursey E, Sünderhauf D, Gaze WH, Westra ER, van Houte S.
Pursey E, et al.
PLoS Pathog. 2018 Jun 14;14(6):e1006990. doi: 10.1371/journal.ppat.1006990. eCollection 2018 Jun.
PLoS Pathog. 2018.
PMID: 29902258
Free PMC article.
No abstract available.
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Bacterial biodiversity drives the evolution of CRISPR-based phage resistance.
Alseth EO, Pursey E, Luján AM, McLeod I, Rollie C, Westra ER.
Alseth EO, et al. Among authors: pursey e.
Nature. 2019 Oct;574(7779):549-552. doi: 10.1038/s41586-019-1662-9. Epub 2019 Oct 23.
Nature. 2019.
PMID: 31645729
Free PMC article.
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CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogens.
Pursey E, Dimitriu T, Paganelli FL, Westra ER, van Houte S.
Pursey E, et al.
Philos Trans R Soc Lond B Biol Sci. 2022 Jan 17;377(1842):20200464. doi: 10.1098/rstb.2020.0464. Epub 2021 Nov 29.
Philos Trans R Soc Lond B Biol Sci. 2022.
PMID: 34839714
Free PMC article.
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Transient eco-evolutionary dynamics early in a phage epidemic have strong and lasting impact on the long-term evolution of bacterial defences.
Watson BNJ, Pursey E, Gandon S, Westra ER.
Watson BNJ, et al. Among authors: pursey e.
PLoS Biol. 2023 Sep 15;21(9):e3002122. doi: 10.1371/journal.pbio.3002122. eCollection 2023 Sep.
PLoS Biol. 2023.
PMID: 37713428
Free PMC article.
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