Bitler BG - Search Results

1

Novel chromobox 2 inhibitory peptide decreases tumor progression.

Brubaker LW, Backos DS, Nguyen VT, Reigan P, Yamamoto TM, Woodruff ER, Iwanaga R, Wempe MF, Kumar V, Persenaire C, Watson ZL, Bitler BG. Brubaker LW, et al. Among authors: bitler bg. Expert Opin Ther Targets. 2023 Apr-May;27(4-5):361-371. doi: 10.1080/14728222.2023.2218614. Epub 2023 May 27. Expert Opin Ther Targets. 2023. PMID: 37243607

2

Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.

Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Aird KM, et al. Among authors: bitler bg. Cell Rep. 2013 Apr 25;3(4):1252-65. doi: 10.1016/j.celrep.2013.03.004. Epub 2013 Apr 4. Cell Rep. 2013. PMID: 23562156 Free PMC article.

3

SWI/SNF catalytic subunits' switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells.

Wu S, Fatkhutdinov N, Fukumoto T, Bitler BG, Park PH, Kossenkov AV, Trizzino M, Tang HY, Zhang L, Gardini A, Speicher DW, Zhang R. Wu S, et al. Among authors: bitler bg. Nat Commun. 2018 Oct 8;9(1):4116. doi: 10.1038/s41467-018-06656-6. Nat Commun. 2018. PMID: 30297712 Free PMC article.

4

Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Tu Z, et al. Among authors: bitler bg. Dev Cell. 2011 Dec 13;21(6):1077-91. doi: 10.1016/j.devcel.2011.10.010. Epub 2011 Dec 1. Dev Cell. 2011. PMID: 22137763 Free PMC article.

5

A high-content screening assay for small-molecule modulators of oncogene-induced senescence.

Bitler BG, Fink LS, Wei Z, Peterson JR, Zhang R. Bitler BG, et al. J Biomol Screen. 2013 Oct;18(9):1054-61. doi: 10.1177/1087057113491827. Epub 2013 Jun 3. J Biomol Screen. 2013. PMID: 23733845 Free PMC article.

6

HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci.

Aird KM, Iwasaki O, Kossenkov AV, Tanizawa H, Fatkhutdinov N, Bitler BG, Le L, Alicea G, Yang TL, Johnson FB, Noma KI, Zhang R. Aird KM, et al. Among authors: bitler bg. J Cell Biol. 2016 Nov 7;215(3):325-334. doi: 10.1083/jcb.201608026. Epub 2016 Oct 31. J Cell Biol. 2016. PMID: 27799366 Free PMC article.

7

Anti-cancer therapies that utilize cell penetrating peptides.

Bitler BG, Schroeder JA. Bitler BG, et al. Recent Pat Anticancer Drug Discov. 2010 Jun;5(2):99-108. doi: 10.2174/157489210790936252. Recent Pat Anticancer Drug Discov. 2010. PMID: 19961434 Free PMC article. Review.

8

The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level.

Goldman AR, Bitler BG, Schug Z, Conejo-Garcia JR, Zhang R, Speicher DW. Goldman AR, et al. Among authors: bitler bg. Mol Cell Proteomics. 2016 Nov;15(11):3348-3360. doi: 10.1074/mcp.M116.062539. Epub 2016 Sep 21. Mol Cell Proteomics. 2016. PMID: 27654507 Free PMC article.

9

Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy.

Li J, Wang W, Zhang Y, Cieślik M, Guo J, Tan M, Green MD, Wang W, Lin H, Li W, Wei S, Zhou J, Li G, Jing X, Vatan L, Zhao L, Bitler B, Zhang R, Cho KR, Dou Y, Kryczek I, Chan TA, Huntsman D, Chinnaiyan AM, Zou W. Li J, et al. J Clin Invest. 2020 May 1;130(5):2712-2726. doi: 10.1172/JCI134402. J Clin Invest. 2020. PMID: 32027624 Free PMC article.

10

ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.

Li H, Bitler BG, Vathipadiekal V, Maradeo ME, Slifker M, Creasy CL, Tummino PJ, Cairns P, Birrer MJ, Zhang R. Li H, et al. Among authors: bitler bg. Cancer Prev Res (Phila). 2012 Mar;5(3):484-91. doi: 10.1158/1940-6207.CAPR-11-0414. Epub 2011 Dec 5. Cancer Prev Res (Phila). 2012. PMID: 22144423 Free PMC article.

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