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Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer.
Strating E, Verhagen MP, Wensink E, Dünnebach E, Wijler L, Aranguren I, De la Cruz AS, Peters NA, Hageman JH, van der Net MMC, van Schelven S, Laoukili J, Fodde R, Roodhart J, Nierkens S, Snippert H, Gloerich M, Rinkes IB, Elias SG, Kranenburg O. Strating E, et al. Among authors: kranenburg o. Front Immunol. 2023 May 16;14:1053920. doi: 10.3389/fimmu.2023.1053920. eCollection 2023. Front Immunol. 2023. PMID: 37261365 Free PMC article.
Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.
Vellinga TT, den Uil S, Rinkes IH, Marvin D, Ponsioen B, Alvarez-Varela A, Fatrai S, Scheele C, Zwijnenburg DA, Snippert H, Vermeulen L, Medema JP, Stockmann HB, Koster J, Fijneman RJ, de Rooij J, Kranenburg O. Vellinga TT, et al. Among authors: kranenburg o. Oncogene. 2016 Oct 6;35(40):5263-5271. doi: 10.1038/onc.2016.60. Epub 2016 Mar 21. Oncogene. 2016. PMID: 26996663
Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.
Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A. Matondo RB, et al. Among authors: kranenburg o. Oncotarget. 2016 Aug 23;7(34):54662-54675. doi: 10.18632/oncotarget.9952. Oncotarget. 2016. PMID: 27323406 Free PMC article.
181 results