Vedanayagam J - Search Results

1

Essential and recurrent roles for hairpin RNAs in silencing de novo sex chromosome conflict in Drosophila simulans.

Vedanayagam J, Herbette M, Mudgett H, Lin CJ, Lai CM, McDonough-Goldstein C, Dorus S, Loppin B, Meiklejohn C, Dubruille R, Lai EC. Vedanayagam J, et al. PLoS Biol. 2023 Jun 8;21(6):e3002136. doi: 10.1371/journal.pbio.3002136. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37289846 Free PMC article.

2

The hpRNA/RNAi Pathway Is Essential to Resolve Intragenomic Conflict in the Drosophila Male Germline.

Lin CJ, Hu F, Dubruille R, Vedanayagam J, Wen J, Smibert P, Loppin B, Lai EC. Lin CJ, et al. Among authors: vedanayagam j. Dev Cell. 2018 Aug 6;46(3):316-326.e5. doi: 10.1016/j.devcel.2018.07.004. Dev Cell. 2018. PMID: 30086302 Free PMC article.

3

Rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressors.

Vedanayagam J, Lin CJ, Lai EC. Vedanayagam J, et al. Nat Ecol Evol. 2021 Dec;5(12):1613-1623. doi: 10.1038/s41559-021-01592-z. Epub 2021 Dec 3. Nat Ecol Evol. 2021. PMID: 34862477 Free PMC article.

4

The m⁶A pathway facilitates sex determination in Drosophila.

Kan L, Grozhik AV, Vedanayagam J, Patil DP, Pang N, Lim KS, Huang YC, Joseph B, Lin CJ, Despic V, Guo J, Yan D, Kondo S, Deng WM, Dedon PC, Jaffrey SR, Lai EC. Kan L, et al. Among authors: vedanayagam j. Nat Commun. 2017 Jul 4;8:15737. doi: 10.1038/ncomms15737. Nat Commun. 2017. PMID: 28675155 Free PMC article.

5

New genes often acquire male-specific functions but rarely become essential in Drosophila.

Kondo S, Vedanayagam J, Mohammed J, Eizadshenass S, Kan L, Pang N, Aradhya R, Siepel A, Steinhauer J, Lai EC. Kondo S, et al. Among authors: vedanayagam j. Genes Dev. 2017 Sep 15;31(18):1841-1846. doi: 10.1101/gad.303131.117. Genes Dev. 2017. PMID: 29051389 Free PMC article.

6

Gene flow mediates the role of sex chromosome meiotic drive during complex speciation.

Meiklejohn CD, Landeen EL, Gordon KE, Rzatkiewicz T, Kingan SB, Geneva AJ, Vedanayagam JP, Muirhead CA, Garrigan D, Stern DL, Presgraves DC. Meiklejohn CD, et al. Among authors: vedanayagam jp. Elife. 2018 Dec 13;7:e35468. doi: 10.7554/eLife.35468. Elife. 2018. PMID: 30543325 Free PMC article.

7

Evolution of genome structure in the Drosophila simulans species complex.

Chakraborty M, Chang CH, Khost DE, Vedanayagam J, Adrion JR, Liao Y, Montooth KL, Meiklejohn CD, Larracuente AM, Emerson JJ. Chakraborty M, et al. Among authors: vedanayagam j. Genome Res. 2021 Mar;31(3):380-396. doi: 10.1101/gr.263442.120. Epub 2021 Feb 9. Genome Res. 2021. PMID: 33563718 Free PMC article.

8

Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis.

Vedanayagam J, Chatila WK, Aksoy BA, Majumdar S, Skanderup AJ, Demir E, Schultz N, Sander C, Lai EC. Vedanayagam J, et al. Nat Commun. 2019 Aug 15;10(1):3682. doi: 10.1038/s41467-019-11610-1. Nat Commun. 2019. PMID: 31417090 Free PMC article.

9

Regulated dicing of pre-mir-144 via reshaping of its terminal loop.

Shang R, Kretov DA, Adamson SI, Treiber T, Treiber N, Vedanayagam J, Chuang JH, Meister G, Cifuentes D, Lai EC. Shang R, et al. Among authors: vedanayagam j. Nucleic Acids Res. 2022 Jul 22;50(13):7637-7654. doi: 10.1093/nar/gkac568. Nucleic Acids Res. 2022. PMID: 35801921 Free PMC article.

10

Genome diversity and divergence in Drosophila mauritiana: multiple signatures of faster X evolution.

Garrigan D, Kingan SB, Geneva AJ, Vedanayagam JP, Presgraves DC. Garrigan D, et al. Among authors: vedanayagam jp. Genome Biol Evol. 2014 Sep 4;6(9):2444-58. doi: 10.1093/gbe/evu198. Genome Biol Evol. 2014. PMID: 25193308 Free PMC article.

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