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TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.
Qu B, Miskey C, Gömer A, Kleinert RDV, Ibanez SC, Eberle R, Ebenig A, Postmus D, Nocke MK, Herrmann M, Itotia TK, Herrmann ST, Heinen N, Höck S, Hastert FD, von Rhein C, Schürmann C, Li X, van Zandbergen G, Widera M, Ciesek S, Schnierle BS, Tarr AW, Steinmann E, Goffinet C, Pfaender S, Locker JK, Mühlebach MD, Todt D, Brown RJP. Qu B, et al. Among authors: van zandbergen g. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2407437121. doi: 10.1073/pnas.2407437121. Epub 2024 May 30. Proc Natl Acad Sci U S A. 2024. PMID: 38814864
Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate.
Baars I, Jaedtka M, Dewitz LA, Fu Y, Franz T, Mohr J, Gintschel P, Berlin H, Degen A, Freier S, Rygol S, Schraven B, Kahlfuß S, van Zandbergen G, Müller AJ. Baars I, et al. Among authors: van zandbergen g. JCI Insight. 2023 Jul 24;8(14):e169020. doi: 10.1172/jci.insight.169020. JCI Insight. 2023. PMID: 37310793 Free PMC article.
Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response.
Roßmann L, Bagola K, Stephen T, Gerards AL, Walber B, Ullrich A, Schülke S, Kamp C, Spreitzer I, Hasan M, David-Watine B, Shorte SL, Bastian M, van Zandbergen G. Roßmann L, et al. Among authors: van zandbergen g. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2103651118. doi: 10.1073/pnas.2103651118. Proc Natl Acad Sci U S A. 2021. PMID: 34561306 Free PMC article.
Enhanced activation of blood neutrophils and monocytes in patients with Ethiopian localized cutaneous leishmaniasis in response to Leishmania aethiopica Neutrophil activation in Ethiopian cutaneous leishmaniasis.
Chanyalew M, Abebe M, Endale B, Girma S, Tasew G, Bobosha K, Zewide M, Howe R, van Zandbergen G, Ritter U, Gadisa E, Aseffa A, Laskay T. Chanyalew M, et al. Among authors: van zandbergen g. Acta Trop. 2021 Aug;220:105967. doi: 10.1016/j.actatropica.2021.105967. Epub 2021 May 21. Acta Trop. 2021. PMID: 34029532
Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.
Chansard A, Dubrulle N, Poujol de Molliens M, Falanga PB, Stephen T, Hasan M, van Zandbergen G, Aulner N, Shorte SL, David-Watine B; Milieu Intérieur Consortium. Chansard A, et al. Among authors: van zandbergen g. Front Immunol. 2021 Apr 26;12:685768. doi: 10.3389/fimmu.2021.685768. eCollection 2021. Front Immunol. 2021. PMID: 33981321 Free PMC article.
74 results