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Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction.
ChemMedChem. 2024 Apr 16;19(8):e202300648. doi: 10.1002/cmdc.202300648. Epub 2024 Mar 5.
ChemMedChem. 2024.
PMID: 38300970
Navigating α-Synuclein Aggregation Inhibition: Methods, Mechanisms, and Molecular Targets.
Galkin M, Priss A, Kyriukha Y, Shvadchak V.
Galkin M, et al. Among authors: kyriukha y.
Chem Rec. 2024 Feb;24(2):e202300282. doi: 10.1002/tcr.202300282. Epub 2023 Nov 2.
Chem Rec. 2024.
PMID: 37919046
Review.
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The PALB2 DNA-binding domain is an intrinsically disordered recombinase.
Kyriukha Y, Watkins MB, Redington JM, Dastvan R, Uversky VN, Hopkins J, Pozzi N, Korolev S.
Kyriukha Y, et al.
Res Sq [Preprint]. 2023 Sep 18:rs.3.rs-3235465. doi: 10.21203/rs.3.rs-3235465/v1.
Res Sq. 2023.
PMID: 37790553
Free PMC article.
Preprint.
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The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.
Kyriukha Y, Watkins MB, Redington JM, Dastvan R, Uversky VN, Hopkins JB, Pozzi N, Korolev S.
Kyriukha Y, et al.
bioRxiv [Preprint]. 2024 May 29:2023.06.01.543259. doi: 10.1101/2023.06.01.543259.
bioRxiv. 2024.
PMID: 37333393
Free PMC article.
Preprint.
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α-Synuclein Dimers as Potent Inhibitors of Fibrillization.
Kyriukha YA, Afitska K, Kurochka AS, Sachan S, Galkin M, Yushchenko DA, Shvadchak VV.
Kyriukha YA, et al.
J Med Chem. 2019 Nov 27;62(22):10342-10351. doi: 10.1021/acs.jmedchem.9b01400. Epub 2019 Nov 4.
J Med Chem. 2019.
PMID: 31625739
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