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Engineered DNA ligases with improved activities in vitro.
Wilson RH, Morton SK, Deiderick H, Gerth ML, Paul HA, Gerber I, Patel A, Ellington AD, Hunicke-Smith SP, Patrick WM. Wilson RH, et al. Among authors: patrick wm. Protein Eng Des Sel. 2013 Jul;26(7):471-8. doi: 10.1093/protein/gzt024. Epub 2013 Jun 10. Protein Eng Des Sel. 2013. PMID: 23754529
Enzyme evolution: innovation is easy, optimization is complicated.
Newton MS, Arcus VL, Gerth ML, Patrick WM. Newton MS, et al. Among authors: patrick wm. Curr Opin Struct Biol. 2018 Feb;48:110-116. doi: 10.1016/j.sbi.2017.11.007. Epub 2017 Dec 5. Curr Opin Struct Biol. 2018. PMID: 29207314 Free article. Review.
62 results