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Discovery and Targeting of a Noncanonical Mechanism of Sarcoma Resistance to ADI-PEG20 Mediated by the Microenvironment.
Rogers LC, Kremer JC, Brashears CB, Lin Z, Hu Z, Bastos ACS, Baker A, Fettig N, Zhou D, Shoghi KI, Dehner CA, Chrisinger JSA, Bomalaski JS, Garcia BA, Oyama T, White EP, Van Tine BA. Rogers LC, et al. Among authors: hu z. Clin Cancer Res. 2023 Aug 15;29(16):3189-3202. doi: 10.1158/1078-0432.CCR-22-2642. Clin Cancer Res. 2023. PMID: 37339179 Free PMC article.
Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response.
Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Hu ZS, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan JL, Ganesan S, Chan CS, Mehnert JM, Lattime EC, White E. Poillet-Perez L, et al. Nat Cancer. 2020 Sep;1(9):923-934. doi: 10.1038/s43018-020-00110-7. Epub 2020 Sep 18. Nat Cancer. 2020. PMID: 34476408 Free PMC article.
Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival.
Yang Y, Gomez M, Marsh T, Poillet-Perez L, Sawant A, Chen L, Park NR, Jackson SR, Hu Z, Alon N, Liu C, Debnath J, Guan JL, Davidson S, Verzi M, White E. Yang Y, et al. Among authors: hu z. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2202016119. doi: 10.1073/pnas.2202016119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537042 Free PMC article.
Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival.
Liao Y, Chu HP, Hu Z, Merkin JJ, Chen J, Liu Z, Degenhardt K, White E, Ryazanov AG. Liao Y, et al. Among authors: hu z. J Biol Chem. 2016 Sep 9;291(37):19545-57. doi: 10.1074/jbc.M116.724856. Epub 2016 Jul 27. J Biol Chem. 2016. PMID: 27466362 Free PMC article.
Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response.
Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Hu ZS, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan JL, Ganesan S, Chan CS, Mehnert JM, Lattime EC, White E. Poillet-Perez L, et al. Nat Cancer. 2021 Sep;2(9):994. doi: 10.1038/s43018-021-00252-2. Nat Cancer. 2021. PMID: 35121870 No abstract available.
Autophagy maintains tumour growth through circulating arginine.
Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E. Poillet-Perez L, et al. Nature. 2018 Nov;563(7732):569-573. doi: 10.1038/s41586-018-0697-7. Epub 2018 Nov 14. Nature. 2018. PMID: 30429607 Free PMC article.
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