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The energy landscape for R-loop formation by the CRISPR-Cas Cascade complex.
Kauert DJ, Madariaga-Marcos J, Rutkauskas M, Wulfken A, Songailiene I, Sinkunas T, Siksnys V, Seidel R. Kauert DJ, et al. Among authors: sinkunas t. Nat Struct Mol Biol. 2023 Jul;30(7):1040-1047. doi: 10.1038/s41594-023-01019-2. Epub 2023 Jul 6. Nat Struct Mol Biol. 2023. PMID: 37415009
Cas3 nuclease-helicase activity assays.
Sinkunas T, Gasiunas G, Siksnys V. Sinkunas T, et al. Methods Mol Biol. 2015;1311:277-91. doi: 10.1007/978-1-4939-2687-9_18. Methods Mol Biol. 2015. PMID: 25981480
Decision-Making in Cascade Complexes Harboring crRNAs of Altered Length.
Songailiene I, Rutkauskas M, Sinkunas T, Manakova E, Wittig S, Schmidt C, Siksnys V, Seidel R. Songailiene I, et al. Among authors: sinkunas t. Cell Rep. 2019 Sep 17;28(12):3157-3166.e4. doi: 10.1016/j.celrep.2019.08.033. Cell Rep. 2019. PMID: 31533038 Free PMC article.
15 results