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Telomere and ATM Dynamics in CD4 T-Cell Depletion in Active and Virus-Suppressed HIV Infections.
Khanal S, Tang Q, Cao D, Zhao J, Nguyen LN, Oyedeji OS, Dang X, Nguyen LNT, Schank M, Thakuri BKC, Ogbu C, Morrison ZD, Wu XY, Zhang Z, He Q, El Gazzar M, Li Z, Ning S, Wang L, Moorman JP, Yao ZQ. Khanal S, et al. Among authors: nguyen lnt, nguyen ln. J Virol. 2020 Oct 27;94(22):e01061-20. doi: 10.1128/JVI.01061-20. Print 2020 Oct 27. J Virol. 2020. PMID: 32907975 Free PMC article.
Mitochondrial topoisomerase 1 inhibition induces topological DNA damage and T cell dysfunction in patients with chronic viral infection.
Dang X, Cao D, Zhao J, Schank M, Khanal S, Nguyen LNT, Wu XY, Zhang Y, Zhang J, Jiang Y, Ning S, Wang L, El Gazzar M, Moorman JP, Yao ZQ. Dang X, et al. Among authors: nguyen lnt. Front Cell Infect Microbiol. 2022 Nov 3;12:1026293. doi: 10.3389/fcimb.2022.1026293. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36405960 Free PMC article.
ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy.
Zhao J, Nguyen LNT, Nguyen LN, Dang X, Cao D, Khanal S, Schank M, Thakuri BKC, Ogbu SC, Morrison ZD, Wu XY, Li Z, Zou Y, El Gazzar M, Ning S, Wang L, Moorman JP, Yao ZQ. Zhao J, et al. Among authors: nguyen lnt, nguyen ln. Front Immunol. 2019 Nov 5;10:2531. doi: 10.3389/fimmu.2019.02531. eCollection 2019. Front Immunol. 2019. PMID: 31781094 Free PMC article.
Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection.
Dang X, Ogbu SC, Zhao J, Nguyen LNT, Cao D, Nguyen LN, Khanal S, Schank M, Thakuri BKC, Wu XY, Morrison ZD, Zhang J, Li Z, El Gazzar M, Ning S, Wang L, Wang Z, Moorman JP, Yao ZQ. Dang X, et al. Among authors: nguyen lnt, nguyen ln. Cell Death Dis. 2020 Mar 19;11(3):196. doi: 10.1038/s41419-020-2395-2. Cell Death Dis. 2020. PMID: 32193368 Free PMC article.
Long noncoding RNA HOTAIRM1 promotes myeloid-derived suppressor cell expansion and suppressive functions through up-regulating HOXA1 expression during latent HIV infection.
Zhang J, Thakuri BKC, Zhao J, Nguyen LN, Nguyen LNT, Cao D, Dang X, Khanal S, Schank M, Lu Z, Wu XY, Morrison ZD, Gazzar ME, Li Z, Jiang Y, Ning S, Wang L, Moorman JP, Yao ZQ. Zhang J, et al. Among authors: nguyen lnt, nguyen ln. AIDS. 2020 Dec 1;34(15):2211-2221. doi: 10.1097/QAD.0000000000002700. AIDS. 2020. PMID: 33048872 Free PMC article.
Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway.
Schank M, Zhao J, Wang L, Li Z, Cao D, Nguyen LN, Dang X, Khanal S, Nguyen LNT, Thakuri BKC, Ogbu SC, Lu Z, Zhang J, Wu XY, Morrison ZD, El Gazzar M, Ning S, Moorman JP, Yao ZQ. Schank M, et al. Among authors: nguyen lnt, nguyen ln. Cell Death Dis. 2020 Dec 2;11(12):1030. doi: 10.1038/s41419-020-03238-7. Cell Death Dis. 2020. PMID: 33268822 Free PMC article.
31 results