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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition.
Lipinski B, Unmuth L, Arras P, Becker S, Bauer C, Toleikis L, Krah S, Doerner A, Yanakieva D, Boje AS, Klausz K, Peipp M, Siegmund V, Evers A, Kolmar H, Pekar L, Zielonka S. Lipinski B, et al. Among authors: doerner a. MAbs. 2023 Jan-Dec;15(1):2236265. doi: 10.1080/19420862.2023.2236265. MAbs. 2023. PMID: 37469014 Free PMC article.
Aptamers Binding to c-Met Inhibiting Tumor Cell Migration.
Piater B, Doerner A, Guenther R, Kolmar H, Hock B. Piater B, et al. Among authors: doerner a. PLoS One. 2015 Dec 11;10(12):e0142412. doi: 10.1371/journal.pone.0142412. eCollection 2015. PLoS One. 2015. PMID: 26658271 Free PMC article.
Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates.
Sellmann C, Doerner A, Knuehl C, Rasche N, Sood V, Krah S, Rhiel L, Messemer A, Wesolowski J, Schuette M, Becker S, Toleikis L, Kolmar H, Hock B. Sellmann C, et al. Among authors: doerner a. J Biol Chem. 2016 Nov 25;291(48):25106-25119. doi: 10.1074/jbc.M116.753491. Epub 2016 Sep 30. J Biol Chem. 2016. PMID: 27694443 Free PMC article.
Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries.
Schröter C, Beck J, Krah S, Zielonka S, Doerner A, Rhiel L, Günther R, Toleikis L, Kolmar H, Hock B, Becker S. Schröter C, et al. Among authors: doerner a. Mol Biotechnol. 2018 Oct;60(10):727-735. doi: 10.1007/s12033-018-0109-0. Mol Biotechnol. 2018. PMID: 30076531 Free PMC article.
Intein mediated high throughput screening for bispecific antibodies.
Hofmann T, Schmidt J, Ciesielski E, Becker S, Rysiok T, Schütte M, Toleikis L, Kolmar H, Doerner A. Hofmann T, et al. Among authors: doerner a. MAbs. 2020 Jan-Dec;12(1):1731938. doi: 10.1080/19420862.2020.1731938. MAbs. 2020. PMID: 32151188 Free PMC article.
Antibody display technologies: selecting the cream of the crop.
Valldorf B, Hinz SC, Russo G, Pekar L, Mohr L, Klemm J, Doerner A, Krah S, Hust M, Zielonka S. Valldorf B, et al. Among authors: doerner a. Biol Chem. 2021 Mar 23;403(5-6):455-477. doi: 10.1515/hsz-2020-0377. Print 2022 Apr 26. Biol Chem. 2021. PMID: 33759431 Free article. Review.
79 results