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Page 1
Systematic Approach Revealed SERPING1 Splicing-Affecting Variants to be Highly Represented in the Czech National HAE Cohort.
Grombirikova H, Bily V, Soucek P, Kramarek M, Hakl R, Ballonova L, Ravcukova B, Ricna D, Kozena K, Kratochvilova L, Sobotkova M, Zachova R, Kuklinek P, Kralickova P, Krcmova I, Hanzlikova J, Vachova M, Krystufkova O, Dankova E, Jesenak M, Novackova M, Svoboda M, Litzman J, Freiberger T. Grombirikova H, et al. Among authors: hakl r. J Clin Immunol. 2023 Nov;43(8):1974-1991. doi: 10.1007/s10875-023-01565-w. Epub 2023 Aug 25. J Clin Immunol. 2023. PMID: 37620742 Free PMC article.
Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity.
Ballonová L, Souček P, Slanina P, Réblová K, Zapletal O, Vlková M, Hakl R, Bíly V, Grombiříková H, Svobodová E, Kulíšková P, Štíchová J, Sobotková M, Zachová R, Hanzlíková J, Vachová M, Králíčková P, Krčmová I, Jeseňák M, Freiberger T. Ballonová L, et al. Among authors: hakl r. Front Genet. 2023 Jul 4;14:1123914. doi: 10.3389/fgene.2023.1123914. eCollection 2023. Front Genet. 2023. PMID: 37470035 Free PMC article.
Histamine intolerance.
Hakl R, Litzman J. Hakl R, et al. Vnitr Lek. 2023 Winter;69(1):37-40. doi: 10.36290/vnl.2023.005. Vnitr Lek. 2023. PMID: 36931880 Review. English.
An investigational oral plasma kallikrein inhibitor for on-demand treatment of hereditary angioedema: a two-part, randomised, double-blind, placebo-controlled, crossover phase 2 trial.
Aygören-Pürsün E, Zanichelli A, Cohn DM, Cancian M, Hakl R, Kinaciyan T, Magerl M, Martinez-Saguer I, Stobiecki M, Farkas H, Kiani-Alikhan S, Grivcheva-Panovska V, Bernstein JA, Li HH, Longhurst HJ, Audhya PK, Smith MD, Yea CM, Maetzel A, Lee DK, Feener EP, Gower R, Lumry WR, Banerji A, Riedl MA, Maurer M. Aygören-Pürsün E, et al. Among authors: hakl r. Lancet. 2023 Feb 11;401(10375):458-469. doi: 10.1016/S0140-6736(22)02406-0. Lancet. 2023. PMID: 36774155 Clinical Trial.
Risk Factors for Severe COVID-19 and Hospital Admission in Patients With Inborn Errors of Immunity - Results From a Multicenter Nationwide Study.
Milota T, Sobotkova M, Smetanova J, Bloomfield M, Vydlakova J, Chovancova Z, Litzman J, Hakl R, Novak J, Malkusova I, Hanzlikova J, Jilek D, Hutyrova B, Novak V, Krcmova I, Sediva A, Kralickova P. Milota T, et al. Among authors: hakl r. Front Immunol. 2022 Feb 28;13:835770. doi: 10.3389/fimmu.2022.835770. eCollection 2022. Front Immunol. 2022. PMID: 35296097 Free PMC article.
Recombinant human C1 esterase inhibitor for hereditary angioedema attacks: A European registry.
Valerieva A, Staevska MT, Grivcheva-Panovska V, Jesenak M, Kőhalmi KV, Hrubiskova K, Zanichelli A, Bellizzi L, Relan A, Hakl R, Farkas H. Valerieva A, et al. Among authors: hakl r. World Allergy Organ J. 2021 Apr 22;14(4):100535. doi: 10.1016/j.waojou.2021.100535. eCollection 2021 Apr. World Allergy Organ J. 2021. PMID: 33995818 Free PMC article.
Acquired Angioedema with C1 Inhibitor Deficiency: Occurrence, Clinical Features, and Management: A Nationwide Retrospective Study in the Czech Republic Patients.
Sobotkova M, Zachova R, Hakl R, Kuklinek P, Kralickova P, Krcmova I, Hanzlikova J, Vachova M, Bartunkova J. Sobotkova M, et al. Among authors: hakl r. Int Arch Allergy Immunol. 2021;182(7):642-649. doi: 10.1159/000512933. Epub 2021 Jan 20. Int Arch Allergy Immunol. 2021. PMID: 33472202 Free PMC article.
Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial.
Zuraw B, Lumry WR, Johnston DT, Aygören-Pürsün E, Banerji A, Bernstein JA, Christiansen SC, Jacobs JS, Sitz KV, Gower RG, Gagnon R, Wedner HJ, Kinaciyan T, Hakl R, Hanzlíková J, Anderson JT, McNeil DL, Fritz SB, Yang WH, Tachdjian R, Busse PJ, Craig TJ, Li HH, Farkas H, Best JM, Clemons D, Cornpropst M, Dobo SM, Iocca HA, Kargl D, Nagy E, Murray SC, Collis P, Sheridan WP, Maurer M, Riedl MA. Zuraw B, et al. Among authors: hakl r. J Allergy Clin Immunol. 2021 Jul;148(1):164-172.e9. doi: 10.1016/j.jaci.2020.10.015. Epub 2020 Oct 21. J Allergy Clin Immunol. 2021. PMID: 33098856 Free article. Clinical Trial.
21 results