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C-type natriuretic peptide induces inotropic and lusitropic effects in human 3D-engineered cardiac tissue: Implications for the regulation of cardiac function in humans.
Exp Physiol. 2023 Sep;108(9):1172-1188. doi: 10.1113/EP091303. Epub 2023 Jul 26.
Exp Physiol. 2023.
PMID: 37493451
Free PMC article.
The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs.
Diness JG, Kirchhoff JE, Speerschneider T, Abildgaard L, Edvardsson N, Sørensen US, Grunnet M, Bentzen BH.
Diness JG, et al. Among authors: kirchhoff je.
Front Pharmacol. 2020 Feb 28;11:159. doi: 10.3389/fphar.2020.00159. eCollection 2020.
Front Pharmacol. 2020.
PMID: 32180722
Free PMC article.
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The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts.
Kirchhoff JE, Skarsfeldt MA, Muthukumarasamy KM, Simó-Vicens R, Bomholtz SH, Abildgaard L, Jespersen T, Sørensen US, Grunnet M, Bentzen BH, Diness JG.
Kirchhoff JE, et al.
Front Pharmacol. 2019 Jun 19;10:668. doi: 10.3389/fphar.2019.00668. eCollection 2019.
Front Pharmacol. 2019.
PMID: 31275147
Free PMC article.
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A new negative allosteric modulator, AP14145, for the study of small conductance calcium-activated potassium (KCa 2) channels.
Simó-Vicens R, Kirchhoff JE, Dolce B, Abildgaard L, Speerschneider T, Sørensen US, Grunnet M, Diness JG, Bentzen BH.
Simó-Vicens R, et al. Among authors: kirchhoff je.
Br J Pharmacol. 2017 Dec;174(23):4396-4408. doi: 10.1111/bph.14043. Epub 2017 Oct 22.
Br J Pharmacol. 2017.
PMID: 28925012
Free PMC article.
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Antiarrhythmic effect of the Ca2+-activated K+ (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation.
Kirchhoff JE, Diness JG, Abildgaard L, Sheykhzade M, Grunnet M, Jespersen T.
Kirchhoff JE, et al.
Pflugers Arch. 2016 Nov;468(11-12):1853-1863. doi: 10.1007/s00424-016-1883-9. Epub 2016 Oct 8.
Pflugers Arch. 2016.
PMID: 27722784
Free PMC article.
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Antiarrhythmic Effect of Either Negative Modulation or Blockade of Small Conductance Ca2+-activated K+ Channels on Ventricular Fibrillation in Guinea Pig Langendorff-perfused Heart.
Diness JG, Kirchhoff JE, Sheykhzade M, Jespersen T, Grunnet M.
Diness JG, et al. Among authors: kirchhoff je.
J Cardiovasc Pharmacol. 2015 Sep;66(3):294-9. doi: 10.1097/FJC.0000000000000278.
J Cardiovasc Pharmacol. 2015.
PMID: 25978690
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Synergistic antiarrhythmic effect of combining inhibition of Ca²⁺-activated K⁺ (SK) channels and voltage-gated Na⁺ channels in an isolated heart model of atrial fibrillation.
Kirchhoff JE, Diness JG, Sheykhzade M, Grunnet M, Jespersen T.
Kirchhoff JE, et al.
Heart Rhythm. 2015 Feb;12(2):409-18. doi: 10.1016/j.hrthm.2014.12.010. Epub 2014 Dec 10.
Heart Rhythm. 2015.
PMID: 25496982
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