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CD8-targeted IL2 unleashes tumor-specific immunity in human cancer tissue by reviving the dysfunctional T cell pool.
Cancer Discov. 2024 Apr 2. doi: 10.1158/2159-8290.CD-23-1263. Online ahead of print.
Cancer Discov. 2024.
PMID: 38563969
Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment.
van der Leun AM, Traets JJH, Vos JL, Elbers JBW, Patiwael S, Qiao X, Machuca-Ostos M, Thommen DS, Haanen JBAG, Schumacher TNM, Zuur CL.
van der Leun AM, et al. Among authors: machuca ostos m.
Cancer Discov. 2023 Oct 5;13(10):2212-2227. doi: 10.1158/2159-8290.CD-22-0851.
Cancer Discov. 2023.
PMID: 37548431
Free PMC article.
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The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4.
Begley V, Corzo D, Jordán-Pla A, Cuevas-Bermúdez A, Miguel-Jiménez L, Pérez-Aguado D, Machuca-Ostos M, Navarro F, Chávez MJ, Pérez-Ortín JE, Chávez S.
Begley V, et al. Among authors: machuca ostos m.
Nucleic Acids Res. 2019 Oct 10;47(18):9524-9541. doi: 10.1093/nar/gkz660.
Nucleic Acids Res. 2019.
PMID: 31392315
Free PMC article.
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