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Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Vande Voorde J, Steven RT, Najumudeen AK, Ford CA, Dexter A, Gonzalez-Fernandez A, Nikula CJ, Xiang Y, Ford L, Maneta Stavrakaki S, Gilroy K, Zeiger LB, Pennel K, Hatthakarnkul P, Elia EA, Nasif A, Murta T, Manoli E, Mason S, Gillespie M, Lannagan TRM, Vlahov N, Ridgway RA, Nixon C, Raven A, Mills M, Athineos D, Kanellos G, Nourse C, Gay DM, Hughes M, Burton A, Yan B, Sellers K, Wu V, De Ridder K, Shokry E, Huerta Uribe A, Clark W, Clark G, Kirschner K, Thienpont B, Li VSW, Maddocks ODK, Barry ST, Goodwin RJA, Kinross J, Edwards J, Yuneva MO, Sumpton D, Takats Z, Campbell AD, Bunch J, Sansom OJ. Vande Voorde J, et al. Among authors: hughes m. Nat Metab. 2023 Aug;5(8):1303-1318. doi: 10.1038/s42255-023-00857-0. Epub 2023 Aug 14. Nat Metab. 2023. PMID: 37580540 Free PMC article.
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.
Leach JDG, Vlahov N, Tsantoulis P, Ridgway RA, Flanagan DJ, Gilroy K, Sphyris N, Vázquez EG, Vincent DF, Faller WJ, Hodder MC, Raven A, Fey S, Najumudeen AK, Strathdee D, Nixon C, Hughes M, Clark W, Shaw R; S:CORT consortium; van Hooff SR, Huels DJ, Medema JP, Barry ST, Frame MC, Unciti-Broceta A, Leedham SJ, Inman GJ, Jackstadt R, Thompson BJ, Campbell AD, Tejpar S, Sansom OJ. Leach JDG, et al. Among authors: hughes m. Nat Commun. 2021 Jun 8;12(1):3464. doi: 10.1038/s41467-021-23717-5. Nat Commun. 2021. PMID: 34103493 Free PMC article.
New Guinea has the world's richest island flora.
Cámara-Leret R, Frodin DG, Adema F, Anderson C, Appelhans MS, Argent G, Arias Guerrero S, Ashton P, Baker WJ, Barfod AS, Barrington D, Borosova R, Bramley GLC, Briggs M, Buerki S, Cahen D, Callmander MW, Cheek M, Chen CW, Conn BJ, Coode MJE, Darbyshire I, Dawson S, Dransfield J, Drinkell C, Duyfjes B, Ebihara A, Ezedin Z, Fu LF, Gideon O, Girmansyah D, Govaerts R, Fortune-Hopkins H, Hassemer G, Hay A, Heatubun CD, Hind DJN, Hoch P, Homot P, Hovenkamp P, Hughes M, Jebb M, Jennings L, Jimbo T, Kessler M, Kiew R, Knapp S, Lamei P, Lehnert M, Lewis GP, Linder HP, Lindsay S, Low YW, Lucas E, Mancera JP, Monro AK, Moore A, Middleton DJ, Nagamasu H, Newman MF, Nic Lughadha E, Melo PHA, Ohlsen DJ, Pannell CM, Parris B, Pearce L, Penneys DS, Perrie LR, Petoe P, Poulsen AD, Prance GT, Quakenbush JP, Raes N, Rodda M, Rogers ZS, Schuiteman A, Schwartsburd P, Scotland RW, Simmons MP, Simpson DA, Stevens P, Sundue M, Testo W, Trias-Blasi A, Turner I, Utteridge T, Walsingham L, Webber BL, Wei R, Weiblen GD, Weigend M, Weston P, de Wilde W, Wilkie P, Wilmot-Dear CM, Wilson HP, Wood JRI, Zhang LB, van Welzen PC. Cámara-Leret R, et al. Among authors: hughes m. Nature. 2020 Aug;584(7822):579-583. doi: 10.1038/s41586-020-2549-5. Epub 2020 Aug 5. Nature. 2020. PMID: 32760001
Characterization of prehistoric flint mine products.
Sieveking Gde G, Craddock PT, Hughes MJ, Bush P, Ferguson J. Sieveking Gde G, et al. Among authors: hughes mj. Nature. 1970 Oct 17;228(5268):251-4. doi: 10.1038/228251a0. Nature. 1970. PMID: 16058488
Skeletal Muscle Mitochondrial Morphology Negatively Affected in Mice Lacking Xin.
Martin G, Al-Sajee D, Gingrich M, Chattha R, Akcan M, Monaco CMF, Hughes MC, Perry CGR, Rebalka IA, Tarnopolsky MA, Hawke TJ. Martin G, et al. Among authors: hughes mc. Biochem Cell Biol. 2024 Jun 6. doi: 10.1139/bcb-2024-0034. Online ahead of print. Biochem Cell Biol. 2024. PMID: 38843556
Comparing Leadership Skills of Senior Emergency Medicine Residents in 3-Year Versus 4-Year Programs During Simulated Pediatric Resuscitation: A Pilot Study.
Schoppel K, Keilman A, Fayyaz J, Padlipsky P, Diaz MCG, Wing R, Hughes M, Franco M, Swinger N, Whitfill T, Walsh B; Improving Pediatric Acute Care Through Simulation (ImPACTS). Schoppel K, et al. Among authors: hughes m. Pediatr Emerg Care. 2024 May 30. doi: 10.1097/PEC.0000000000003216. Online ahead of print. Pediatr Emerg Care. 2024. PMID: 38809592
Intervention to promote adolescents' communication and engagement in diabetes clinic encounters: A pilot randomized controlled trial.
Coyne I, Sleath B, Surdey J, Pembroke S, Hilliard C, Chechalk K, Rafferty S, Rogerson S, Hughes M M, Murphy M, Cody D, Roche E. Coyne I, et al. Among authors: hughes m m. Patient Educ Couns. 2024 May 16;126:108322. doi: 10.1016/j.pec.2024.108322. Online ahead of print. Patient Educ Couns. 2024. PMID: 38772095 Free article.
3,850 results