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CFTR-rich ionocytes mediate chloride absorption across airway epithelia.
Lei L, Traore S, Romano Ibarra GS, Karp PH, Rehman T, Meyerholz DK, Zabner J, Stoltz DA, Sinn PL, Welsh MJ, McCray PB Jr, Thornell IM. Lei L, et al. Among authors: karp ph. J Clin Invest. 2023 Oct 16;133(20):e171268. doi: 10.1172/JCI171268. J Clin Invest. 2023. PMID: 37581935 Free PMC article.
CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo.
Ostedgaard LS, Zabner J, Vermeer DW, Rokhlina T, Karp PH, Stecenko AA, Randak C, Welsh MJ. Ostedgaard LS, et al. Among authors: karp ph. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3093-8. doi: 10.1073/pnas.261714599. Epub 2002 Feb 19. Proc Natl Acad Sci U S A. 2002. PMID: 11854474 Free PMC article.
Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.
Farmen SL, Karp PH, Ng P, Palmer DJ, Koehler DR, Hu J, Beaudet AL, Zabner J, Welsh MJ. Farmen SL, et al. Among authors: karp ph. Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1123-30. doi: 10.1152/ajplung.00049.2005. Epub 2005 Aug 5. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 16085675 Free article.
Differentiation of human airway epithelia is dependent on erbB2.
Vermeer PD, Panko L, Karp P, Lee JH, Zabner J. Vermeer PD, et al. Am J Physiol Lung Cell Mol Physiol. 2006 Aug;291(2):L175-80. doi: 10.1152/ajplung.00547.2005. Epub 2006 Feb 17. Am J Physiol Lung Cell Mol Physiol. 2006. PMID: 16489114 Free article.
56 results