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Glycogen synthase kinase-3β is involved in ligand-dependent activation of transcription and cellular localization of the glucocorticoid receptor.
Rubio-Patiño C, Palmeri CM, Pérez-Perarnau A, Cosialls AM, Moncunill-Massaguer C, González-Gironès DM, Pons-Hernández L, López JM, Ventura F, Gil J, Pons G, Iglesias-Serret D. Rubio-Patiño C, et al. Mol Endocrinol. 2012 Sep;26(9):1508-20. doi: 10.1210/me.2011-1366. Epub 2012 Jul 6. Mol Endocrinol. 2012. PMID: 22771494 Free PMC article.
Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.
Saura-Esteller J, Sánchez-Vera I, Núñez-Vázquez S, Cosialls AM, Gama-Pérez P, Bhosale G, Mendive-Tapia L, Lavilla R, Pons G, Garcia-Roves PM, Duchen MR, Iglesias-Serret D, Gil J. Saura-Esteller J, et al. Among authors: iglesias serret d. Int J Mol Sci. 2021 Jun 6;22(11):6117. doi: 10.3390/ijms22116117. Int J Mol Sci. 2021. PMID: 34204139 Free PMC article.
NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.
Núñez-Vázquez S, Sánchez-Vera I, Saura-Esteller J, Cosialls AM, Noisier AFM, Albericio F, Lavilla R, Pons G, Iglesias-Serret D, Gil J. Núñez-Vázquez S, et al. Among authors: iglesias serret d. FEBS J. 2021 Feb;288(4):1271-1285. doi: 10.1111/febs.15480. Epub 2020 Jul 26. FEBS J. 2021. PMID: 32648994 Free article.
The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.
Cosialls AM, Sánchez-Vera I, Pomares H, Perramon-Andújar J, Sanchez-Esteban S, Palmeri CM, Iglesias-Serret D, Saura-Esteller J, Núñez-Vázquez S, Lavilla R, González-Barca EM, Pons G, Gil J. Cosialls AM, et al. Among authors: iglesias serret d. Biochem Pharmacol. 2020 Oct;180:114198. doi: 10.1016/j.bcp.2020.114198. Epub 2020 Aug 13. Biochem Pharmacol. 2020. PMID: 32798467
Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.
Saura-Esteller J, Sánchez-Vera I, Núñez-Vázquez S, Jabalquinto-Carrasco J, Cosialls AM, Mendive-Tapia L, Kukhtar D, Martínez-Bueno MD, Lavilla R, Cerón J, Artal-Sanz M, Pons G, Iglesias-Serret D, Gil J. Saura-Esteller J, et al. Among authors: iglesias serret d. Apoptosis. 2021 Feb;26(1-2):83-95. doi: 10.1007/s10495-020-01651-z. Epub 2021 Jan 2. Apoptosis. 2021. PMID: 33387147
AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.
Santidrián AF, González-Gironès DM, Iglesias-Serret D, Coll-Mulet L, Cosialls AM, de Frias M, Campàs C, González-Barca E, Alonso E, Labi V, Viollet B, Benito A, Pons G, Villunger A, Gil J. Santidrián AF, et al. Blood. 2010 Oct 21;116(16):3023-32. doi: 10.1182/blood-2010-05-283960. Epub 2010 Jul 27. Blood. 2010. PMID: 20664053 Free article.
31 results