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Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease.
Brain Behav Immun. 2024 May 7;119:919-944. doi: 10.1016/j.bbi.2024.05.006. Online ahead of print.
Brain Behav Immun. 2024.
PMID: 38718909
Free article.
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Daily KP, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan MH, Carafice C, Krause K, McNamara A, Hamilton K, Houle S, Gupta S, Gupta GA, Madhu S, Fitzgerald J, Saadey AA, Laster B, Yan P, Webb A, Zhang X, Pietrzak M, Kokiko-Cochran ON, Ghoneim HE, Amer AO.
Daily KP, et al. Among authors: whitham o.
Alzheimers Res Ther. 2024 Feb 8;16(1):29. doi: 10.1186/s13195-024-01390-2.
Alzheimers Res Ther. 2024.
PMID: 38326859
Free PMC article.
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DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates neuroinflammation and amyloid-β deposition in Alzheimer's disease The Ohio State University College of Medicine.
Daily KP, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan MH, Carafice C, Krause K, McNamara A, Hamilton K, Houle S, Gupta S, Gupta GA, Madhu S, Fitzgerald J, Saadey AA, Laster B, Yan P, Webb A, Zhang X, Pietrzak M, Kokiko-Cochran ON, Ghoneim HE, Amer AO.
Daily KP, et al. Among authors: whitham o.
bioRxiv [Preprint]. 2023 Sep 1:2023.08.30.555526. doi: 10.1101/2023.08.30.555526.
bioRxiv. 2023.
PMID: 37693600
Free PMC article.
Preprint.
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FERONIA functions through Target of Rapamycin (TOR) to negatively regulate autophagy.
Wang P, Clark NM, Nolan TM, Song G, Whitham OG, Liao CY, Montes-Serey C, Bassham DC, Walley JW, Yin Y, Guo H.
Wang P, et al. Among authors: whitham og.
Front Plant Sci. 2022 Aug 23;13:961096. doi: 10.3389/fpls.2022.961096. eCollection 2022.
Front Plant Sci. 2022.
PMID: 36082288
Free PMC article.
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Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Eltobgy MM, Zani A, Kenney AD, Estfanous S, Kim E, Badr A, Carafice C, Daily K, Whitham O, Pietrzak M, Webb A, Kawahara J, Eddy AC, Denz P, Lu M, Kc M, Peeples ME, Li J, Zhu J, Que J, Robinson R, Rosas Mejia O, Rayner RE, Hall-Stoodley L, Seveau S, Gavrilin MA, Zhang X, Thomas J, Kohlmeier JE, Suthar MS, Oltz E, Tedeschi A, Robledo-Avila FH, Partida-Sanchez S, Hemann EA, Abdelrazik E, Forero A, Nimjee SM, Boyaka PN, Cormet-Boyaka E, Yount JS, Amer AO.
Eltobgy MM, et al. Among authors: whitham o.
Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2202012119. doi: 10.1073/pnas.2202012119. Epub 2022 May 19.
Proc Natl Acad Sci U S A. 2022.
PMID: 35588457
Free PMC article.
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Magnesium-specific ring expansion/contraction catalysed by the class II diterpene cyclase from pleuromutilin biosynthesis.
Lemke C, Whitham O, Peters RJ.
Lemke C, et al. Among authors: whitham o.
Org Biomol Chem. 2020 Jul 29;18(29):5586-5588. doi: 10.1039/d0ob01422b.
Org Biomol Chem. 2020.
PMID: 32672326
Free PMC article.
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